Examination of sperm function through proteomics has the potential to improve on conventional semen analysis in the workup of male infertility. Differentially expressed proteins may serve as novel biomarkers in the identification of bilateral varicocele and may help urologists identify better options for clinical management of infertile men.
In 2012 Cleveland Clinic’s IVF laboratory acquired the EmbryoScope®, an incubator with a built-in microscope and high-definition camera that enables more detailed observations on embryo developmental kinetics.
Uterine transplantation was greeted with skepticism eight or nine years ago. Today the procedure offers hope to women with congenital or surgical absence of the uterus.
Genetically testing embryos for devastating conditions like Huntington’s disease before implantation is usually considered acceptable. But selecting embryos based solely on gender touches a nerve for many. Physicians must help patients understand all of the choices and options available to them.
Until recently, women undergoing certain chemotherapy had few options for fertility preservation. Though still experimental, ovarian tissue cryopreservation is being performed under Institutional Review Board-approved protocol with detailed informed consent. To date, at least 26 live births have been recorded worldwide using this technique. Cleveland Clinic now offers ovarian tissue freezing for pediatric and adult populations.
Novel approach to breast cancer treatment may help prevent premature ovarian failure and boost both fertility and survival.