Discover how this novel minimally invasive technique may avoid the potential morbidity associated with a large corneoscleral incision, allowing for rapid visual recovery.
Surgical Head-Scratcher: What to Do When LVOTO Presents with Minimal Hypertrophy?
Patients with LV outflow tract obstruction but little or no LV hypertrophy present a diagnostic dilemma. The best approaches involve tailored diagnostic strategies and repairs aimed at avoiding prosthetic valve replacement.
Breathing Life into the Prospect of Early Detection of Pediatric Fatty Liver Disease
Exhaled breath analysis shows promise for noninvasive diagnosis
Early Brain Injury After SAH: Is Ischemia Happening Faster Than We Imagined?
Recent prospective MRI studies found evidence of early ischemia in two-thirds of patients acutely after SAH. We’re now planning studies aimed at correlating platelet-leukocyte interactions with this MRI evidence of ischemia.
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A Targeted Approach to Tackling Tumors’ Drug Resistance
Cleveland Clinic radiation oncologist Mohamed Abazeed, MD, PhD, is taking an individualized, targeted approach to study mutations that can affect a tumor’s resistance to chemotherapy. With patient-derived cell lines and mouse xenografts, he produces physiologically relevant test beds for improved gene/drug treatment protocols.
Brain Activity After Concussion: fMRI Studies Show a Shift in Activation and a Lasting ‘Neural Signature’
Two recent functional neuroimaging studies advance our understanding of how the brain changes with concussion, raising the prospect of one day using fMRI for disability assessment and rehab planning.
No Laughing Matter: Defining the Role of a New Agent for Pseudobulbar Affect
After making its mark as the first therapy approved for pseudobulbar affect (pathologic laughing and crying) in ALS and MS, Nuedexta is under study for additional uses in a range neurologic diseases.
MP-MRI-US Fusion Targeted Biopsy: A Promising New Diagnostic Tool for Prostate Cancer
Specialized software now combines multiparametric MRI and transrectal ultrasound images to improve targeted biopsy of suspicious lesions. The technology has the potential to significantly improve localization and characterization of prostate cancer when added to a 12-core biopsy.
Case Study: A Role for Vascular Surgery in a Curious Case of Abdominal Pain and Major Weight Loss
Median arcuate ligament syndrome is controversial because of its lack of proved mechanism. The main evidence for it is patients’ relief following release of the median arcuate ligament — typically after a long, agonizing diagnostic journey.
Blood Biomarkers to Guide Surveillance and Treatment of Uveal Melanoma Being Explored
Discover how Cleveland Clinic physicians are hoping to improve survival in uveal melanoma by identifying patients with micrometastases—and suppressing them before they progress to macrometastases.