Deep brain stimulation (DBS) with real time intraoperative MRI lets surgeons assess lead location with anatomic landmarks instead of the microelectrode recording used during awake surgery. The intraoperative imaging allows DBS surgery to be done under general anesthesia, without patients needing to be awake for physiological measurements. Early Cleveland Clinic experience shows DBS leads implanted using intraoperative MRI varied only modestly from target placement, within expected error ranges.
Applying electrical stimulation to the dentatothalamocortical pathway improves motor outcomes and markers of synaptogenesis in rodent models of post-stroke rehab. Work continues toward applications in humans.
Five new technologies — subcutaneous ICDs, contact force ablation catheters, leadless pacemakers, a vagal nerve stimulator and a left atrial appendage occlusion device — are making EP procedures safer and more effective.