18F-fluciclovine PET/CT has the potential to distinguish radiation necrosis from tumor progression in brain tumors previously treated with stereotactic radiosurgery.
A multicenter research team will investigate differences in genetics, epigenetics and cell biology between males and females, with the goal of more-personalized therapy approaches for glioblastoma.
Analysis of a large patient series supports the notion that CT without MRI follow-up is adequate to rule out brain tumor or thrombosis in children with papilledema and normal neurologic findings.
We profile four ongoing Cleveland Clinic-led clinical studies that are evaluating mechanistically diverse strategies to extend survival in patients with this formidable malignancy.
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A review of 240 cases from our experience over eight years finds that outcomes and operative times have improved substantially even as laser ablation is increasingly used to treat metastases and radiation necrosis.
Emerging sex differences in multiple aspects of this lethal brain cancer likely help explain the disease’s more favorable incidence and prognosis in females. And they may point to new targeted therapies.
In patients with newly diagnosed glioblastoma who aren’t candidates for resection, minimally invasive ablative treatment appears to be reasonable initial therapy, a new study suggests.
A leading clinician-researcher profiles clinical trials of mechanistically diverse treatment strategies to combat glioblastoma. All four stem from Cleveland Clinic’s robust translational collaborations in this space.
Neurosurgeon Gene Barnett, MD, MBA, is the 2017 Sones Innovation Award honoree for inventing frameless neuronavigation and leading the development of laser thermal therapy for brain tumors.
No current treatments for primary brain tumors achieve significant direct bloodstream access to the brain. Cleveland Clinic’s involved in a broad range of trials aiming to change that.