Investigators are analyzing microbiomes in several solid tumors. If microbiome elements are involved in carcinogenesis, they could serve as biomarkers for progression and prognosis, as well as therapeutic targets.
Patients with inherited cancer syndromes benefit from a Cleveland Clinic multidisciplinary referral network that provides a formal thyroid cancer screening process.
Charis Eng, MD, PhD, Chair and Director of Cleveland Clinic’s Genomic Medicine Institute, shares her views on genetics-related Top 10 Innovations.
Recording patients’ family medical history and including it in their medical record is important in prevention, risk reduction and early detection of disease.
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As key members of the Center for Personalized Genetic Healthcare, genetic counselors translate complicated data into information patients can readily understand.
Findings of this large registry study of families suggest a more comprehensive care model makes sense for the entire family when one child has autism.
The discovery of cancer-predisposing gene mutations associated with Cowden syndrome and some apparently sporadic thyroid cancers highlights how cellular stress responses can be hijacked by cancer cells to promote their survival.
Cleveland Clinic physicians and scientists release annual Top 10 innovations list, including faster methods of creating vaccines, a process for rewriting genetic code and a water purification system for the developing world.
A Cleveland Clinic study of patients with some features of Cowden syndrome and endometrial cancer shows that certain demographic and clinical features can predict the likelihood of harboring a PTEN or other gene mutation and serve as a catalyst for cancer genetic evaluation.
This clinical study of children with autism and PTEN gene mutations did more than define a unique autism subtype. It’s now sparked one of the first attempts at an individualized gene-based treatment approach to autism.