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OPTIMAL Trial Finds Comparable Outcomes for Two Vaginal Prolapse Surgical Repairs

The OPTIMAL trial found that sacrospinous ligament fixation (SSLF) and uterosacral ligament vaginal vault suspension (ULS) were equally safe and effective in treating vaginal prolapse at two years’ follow-up. Adding perioperative behavioral therapy with pelvic floor muscle training into the mix failed to improve either incontinence symptoms or prolapse outcomes.

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Ovarian Tissue Freezing: An Emerging Option for Fertility Preservation

Until recently, women undergoing certain chemotherapy had few options for fertility preservation. Though still experimental, ovarian tissue cryopreservation is being performed under Institutional Review Board-approved protocol with detailed informed consent. To date, at least 26 live births have been recorded worldwide using this technique. Cleveland Clinic now offers ovarian tissue freezing for pediatric and adult populations.