In recent years, the momentum created by the initial effectiveness of chimeric antigen receptor (CAR) T-cell therapy has prompted team-based research efforts in cellular therapy at Cleveland Clinic.
New Cell Therapies May Hold Key to Treatment of Advanced and Rare Skin Cancers
Clinical trials exploring the use of immunotherapy with adoptive cell transfer for advanced melanoma and Merkel cell carcinoma (MCC) are in development at Cleveland Clinic Cancer Center.
Researchers Unlock Keys to Staging and Risk Stratification of Merkel Cell Carcinoma
Cleveland Clinic Cancer Center investigators have published a body of research that may herald an era of improved staging and risk stratification for patients with Merkel cell carcinoma, utilizing distinct histologic patterns in sentinel lymph node biopsies.
Case Report: Merkel Cell Carcinoma Patients Respond to Investigational Combination Therapy
Cleveland Clinic Cancer Center physicians achieved remission in two patients with refractory advanced Merkel cell carcinoma by using a novel treatment that combines an immune checkpoint inhibitor and oncolytic viral immunotherapy.
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