Black Americans with MS have more severe indicators of clinical disability and pathological disease than their white counterparts, even after adjusting for socioeconomic status, finds a large database study.
Cortical changes other than demyelination appear to exert more influence on conventional MRI modalities, finds a new postmortem MRI study. Better acquisition and post-processing methods are needed.
The lead author of a new consensus statement on deep gray matter injury shares potential implications for the characterization, monitoring and treatment of MS.
People with multiple sclerosis fare about as well as other populations following SARS-CoV-2 infection, but ambulation disability and a few other factors raise the risk of a worse clinical course.
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Magnetic resonance fingerprinting is improving lesion identification in epilepsy, brain microstructure evaluation in MS, and more. Two experts share the essentials on this emerging imaging advancement.
Some 2% to 4% of patients misdiagnosed with multiple sclerosis are eventually diagnosed with a genetic leukodystrophy. A new clinical cohort study offers much-needed guidance to help identify them.
A national survey of people living with MS reveals abundant opportunities for greater education about the FDA approval process and opportunities to bolster patients’ confidence in it.
A pooled analysis of three randomized trials of nabiximols helps lay the groundwork for an FDA submission in 2021. Approval would yield the first novel treatment for spasticity in multiple sclerosis in many years.
This protein shows promise as a biomarker for use in early-stage therapeutic trials, but more work is needed. An expert panel has outlined what should be done next to rapidly realize its potential.
Traditional means of monitoring patients with MS are increasingly inadequate. The director of our MS program discusses emerging technologies and research studies to explore their roles.