Researchers are analyzing gene expression signatures to better predict which therapy will work best for each patient with cancer.
Unlocking Precision Medicine in RVO: When Anti-VEGF Therapy Isn’t Effective
Although anti-VEGF therapy is the current gold-standard treatment for retinal vein occlusion, not all patients respond to it. A study has found that volume of intraretinal fluid, among other factors detectable with optical coherence tomography, may help predict treatment response.
Precision Medicine Approach Needed to Treat Subgroups of Diffuse Large B-Cell Lymphoma
Understanding the molecular features of DLBLC tumors may aid in improving treatment efficacy.
The Case for a Precision Medicine Approach to Training Epilepsy Clinicians
We explain why we’ve launched an Epilepsy Precision Medicine Fellowship and how it’s designed to empower tomorrow’s epileptologists to apply neurogenetics to improve patient care
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Adopting a Precision Medicine Approach to Outcome Prediction in Inflammatory Bowel Disease
A paradigm shift is needed in inflammatory bowel disease, a Cleveland Clinic researcher contends, moving from reactive, symptom-based treatment to predictive biomarkers that forecast disease course and enable personalized, targeted therapies to prevent additional tissue damage.
New Collaboration Moves the Needle on Precision Medicine
Cleveland Clinic teams with PDGx to harness the diagnostic power of liquid biopsy and increase the use of precision diagnostics within the cancer care continuum.
Utility of Genomic-Adjusted Radiation Dose as a Pan-Cancer Predictor of Radiation Therapy Benefit
A group of researchers led by Jacob Scott, MD, DPhil, have validated a quantifiable, genomically guided parameter that serves as a predictor of the therapeutic benefit of RT for each individual patient.
In Search of Disease-Modifying Treatment for Alzheimer’s (Podcast)
Most therapies in development for Alzheimer’s are focused on changing disease biology, with targets ranging from amyloid pathology to inflammation. A leader of our clinical trials program shares an update on drug development and diagnostics.
Identifying Actionable Cancer Mutations
Researchers have developed a personalized genomic medicine platform to identify clinically actionable mutations and accelerate the development of cancer precision medicine protocols.
Affordable Precision Medicine for Critically Ill Infants: The Time Is Now
Improvements in the cost and diagnostic accuracy of whole-exome and whole-genome sequencing are reshaping management of NICU patients. We explore benefits and barriers to use.