The decision to screen for prostate cancer is a complicated one. A Cleveland Clinic medical oncologist discusses overdiagnosis and recommends a new path forward.
When used with positron emission tomography, the agent rhPSMA-7.3 (18F) tags prostate-specific membrane antigen, a protein on the surface of the cancer cells, and identifies it on the scan.
Androgen-receptor (AR) antagonists can alter the metabolism of patients with prostate cancer, shows a recent study. And a transporter protein may become a new therapeutic target for kidney cancer.
Cleveland Clinic is now offering the IsoPSA™ test, a novel prostate-specific antigen assay, for patients with a PSA > 4ng/ml who are facing a decision on prostate biopsy.
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A new test developed at Cleveland Clinic interrogates the HSD3B1 gene to determine if a prostate cancer patient has inherited the adrenal-permissive (1245C) or adrenal-restrictive (1245A) allele. The development of the test is an outgrowth of more than seven years of research at Cleveland Clinic.
Which research results from the American Society for Radiation Oncology’s 2019 annual meeting are the most interesting or clinically relevant? The staff of Cleveland Clinic Cancer Center’s Department of Radiation Oncology picks their Top 10.
What research abstracts presented at this year’s American Society of Clinical Oncology annual meeting will have the biggest potential impact on clinical practice? Cleveland Clinic Cancer Center physicians make their picks.
PD-L2 plays a significant part in prostate cancer immune modulation and could be a worthwhile prognostic biomarker as well as an immune checkpoint inhibition target, according to a large genetic analysis.
The IsoPSA prostate-specific antigen test could reduce unnecessary prostate biopsies by more than 40% while reliably differentiating among high-grade, low-grade and benign disease, a new validation study has found.
Active surveillance is a viable choice for African-American prostate cancer patients with low- or intermediate-risk disease, enabling long treatment-free periods and reasonable post-treatment outcomes, new Cleveland Clinic research shows.