In addition to determining the probability of finding N2 or N3 disease on EBUS-TBNA the model is also able to predict the presence of mediastinal disease when EBUS-TBNA nodal sampling is negative.
The potential for molecular biomarkers to tip the balance from benefit to harm in lung cancer screening and nodule diagnosis and to enhance risk prediction warrants a robust discussion about how we determine their accuracy and readiness for clinical use.
Based on our experience at Cleveland Clinic, we favor centralized management of screening decisions in our health system, detailed and thorough shared decision-making visits with one-year follow up and concrete plans for managing incidental findings.
Cleveland Clinic’s Lung and Heart-Lung Transplant Program has gained significant expertise in the management and successful transplantation of recipients who are older than 65, have concomitant CAD or may need liver-lung or heart-lung transplantation. Here we share some recent experiences with these nonconventional transplant recipient cohorts.
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The first reported use of tissue plasminogen activator to treat a pregnant patient for a complicated parapneumonic pleural effusion has a successful outcome.
Effective PERTs reduce mortality, and the growth of these teams is a good example of how multidisciplinary, coordinated, team-based care can work in a complex setting.
Due to improved industrial hygiene measures, acute beryllium disease has essentially disappeared, but chronic beryllium disease (CBD) continues to affect workers in industries where beryllium is manufactured and processed.
Although asthma remains a clinical diagnosis based on episodic symptoms consistent with airflow obstruction, symptoms alone cannot reliably be used to diagnose the disease or assess its severity and control.
MRSA is an especially ubiquitous pathogen in patients with CF. Risk factors must be evaluated, and strict infection control practices must be in place to prevent MRSA, minimize transmission and optimize CF patient outcomes.
For many years hyaluronan was considered to be inert scaffolding with only a mechanical role in supporting and maintaining tissue structure — essentially a goo. But more recent findings indicate that its role is much broader.