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Cardiac Sarcoidosis: What Do We Know?

Symptomatic cardiac involvement in systemic sarcoidosis occurs in only 2 to 5 percent of patients. The most common manifestations include atrioventricular block, ventricular arrhythmia and heart failure. Experts in the field discuss screening, diagnosis, medical therapy, device/ablation therapy and prognosis.

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Thrombolysis in Submassive Pulmonary Embolism

Which patients with submassive embolism would benefit from thrombolysis, and which patients require only anticoagulant therapy? The answer lies in finding the balance between the potential benefit of thrombolytic therapy — preventing death or hemodynamic collapse — and the numerically low but potentially catastrophic risk of intracranial bleeding.