Cleveland Clinic’s kidney transplant program has a half-century of experience and has performed more than 4,340 transplants. Its innovations are improving wait times and outcomes, and its multiple locations provide national and international access for patients.
The emphasis on quality oversight of kidney transplant programs is increasing, while the national volume of transplants has stagnated. Could there be a connection?
Current induction therapy agents are capable of over-immunosuppression. The new anti-lymphocyte antibody TOL101 targets the αβ chain of the T – cell receptor, making it ideal for interrupting a primary immune response.
Acute allograft injury is a significant factor in late graft loss following kidney transplantation. Cleveland Clinic research into the function of alloreactive CD28- memory CD8 T cells should help in the assessment of rejection and graft injury risk.
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Cleveland Clinic researchers have discovered the first example of a genetic alteration that increases the conversion of precursor steroids to 5α-dihydrotestosterone (DHT), permitting prostate tumors to grow in the absence of gonadal testosterone.
Tubeless percutaneous nephrolithotomy is effective and safe regardless of intraoperative issues that were previously used as exclusionary criteria for this approach.
Results help identify active surveillance candidates