The Case for Complete Mesocolic Excision

Complete mesocolic excision (CME) is a reconceptualized approach to treating colon cancer with the goal of reducing local recurrence and improving survival. This case report describes the successful treatment of an 82-year-old patient using CME, illustrating why the procedure should be routinely performed on patients with colon cancer.

New Guidelines Broaden Patients’ Eligibility for Metabolic and Bariatric Surgery

An international panel of experts has issued new evidence-based guidelines that call for dramatically expanding patients’ eligibility for metabolic and bariatric surgery, including recommending that children and adolescents with obesity be considered for weight-loss surgery under certain conditions. The standards significantly lower the body mass index threshold at which surgery should be considered.

Examining the Issue of Resuscitation Efforts for Patients Awaiting Liver Transplant

To be eligible for liver transplant, many centers request that patients awaiting the potentially life-saving procedure consent to full resuscitation in the event of cardiac or respiratory arrest before, during or after surgery. A Cleveland Clinic study reveals knowledge gaps among caregivers about these resuscitation policies, underscoring the importance of education surrounding end of life.

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Celiac Patients Have Elevated Risk of Developing C. difficile Infection

Patients with celiac disease have a higher incidence of Clostridioides difficile infection than the general public, even after accounting for traditional risk factors for developing the sometimes life-threatening diarrheal infection. The new Cleveland Clinic research that identified the link highlights the need for clinicians to consider a C. difficile diagnosis when evaluating celiac patients with new or recurring diarrhea.

New Insights on Post-Transplant Survival after Acute-on-Chronic Liver Failure

Patients with acute-on-chronic liver failure, even those with advanced-grade disease and circulatory failure requiring multiple vasopressors, can achieve one-year survival rates exceeding 80% following liver transplantation, a large North American multicenter study including Cleveland Clinic researchers has found. But the presence of portal vein thrombosis in patients with the most severe ACLF is cause for caution regarding transplantation.

Intraoperative Calibration Spheres: A Simple, Effective Way to Identify Endoluminal Strictures

Many patients with Crohn’s disease eventually require surgery to resolve fibrotic strictures that develop due to inflammation and repetitive scarring in the small bowel. Cleveland Clinic Inflammatory Bowel Disease Surgery Section Chief Stefan Holubar, MD, MS shares a quick, easy stricture identification and assessment technique using intraoperative calibration spheres.

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