Cleveland Clinic researchers and their colleagues are developing digital replicas of real communities, including biological, social and geographic data. Modeling neighborhoods will help identify effective ways to eliminate place-based health inequalities, which disproportionately affect minorities and people with low incomes.Read More
Where We’re Headed with Vaccine Research: A Conversation with Ted Ross, PhD
The renowned virologist, who is Cleveland Clinic’s new Global Director of Vaccine Development, discusses his plans and priorities for the research post.
Novel Technologies Elucidate Underlying Causes of Exercise’s Benefit to the Heart
A preclinical study shows how a key molecular regulator of cardiac remodeling translates to downstream local tissue-level changes, illuminating the mechanisms of exercise-induced cardiac benefits.
Monkeypox Vaccines: What You Need to Know
Distribution of vaccines to protect against the growing mpox outbreak is underway, but questions remain about supply, effectiveness and adverse events. Here’s the latest information, with expert commentary from Ted M. Ross, PhD, Cleveland Clinic’s Global Director of Vaccine Development.
Research Aims to Prevent Future Pandemics
Two Cleveland Clinic Lerner Research Institute scientists are part of a national consortium developing new antiviral drugs to combat COVID-19 and prevent future pandemics.
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Who Will Respond to Migraine Preventive Therapy? Clinical-Genetic Research Collaborative Aims to Find Out
Interdisciplinary researchers are developing a model to predict patients’ response to costly CGRP-inhibiting monoclonal antibodies by pairing a polygenic risk score with demographic and clinical factors.
New Research Collaborative Aims to Close Minority Health Disparities
Cleveland Clinic researchers are organizing the Latino Epidemiology Cohort, a consortium that will investigate disease causes, risk and outcomes in underrepresented communities, initially focusing on Parkinson’s disease and colorectal cancer.
Platelet Olfactory Receptor Identified as Possible AAA Biomarker and Treatment Target
Blocking a newly discovered olfactory membrane receptor has been shown to reduce platelet reactivity in abdominal aortic aneurysms (AAAs), raising the prospect of therapeutic targeting to stop AAA progression.
Pair of NIH Grants to Probe Multiple Sclerosis Pathogenesis on Two Fronts
One of our neuroscientists is investigating a potential link between the circadian cycle and remyelination as well as exploring the molecular basis of thalamic volume atrophy.
Salivary miRNAs Show Potential as Noninvasive Biomarkers of Hepatocellular Carcinoma
MicroRNA molecules associated with hepatocellular carcinoma are present and detectable in saliva and hold promise as highly sensitive and noninvasive biomarkers of the disease, Cleveland Clinic investigators have found.
SARS-CoV-2 Infection During Pregnancy Creates Immune Changes
Cleveland Clinic researchers investigated how COVID-19 infection during pregnancy affects mothers and their infants. The results indicate the need for long-term follow-up to catch any unforeseen health conditions related to the infection.