Integrating advanced microscopy techniques with AI-fueled computational imaging promises to capture brain activity with the depth and speed needed to advance understanding of neurological diseases.
Read MoreResearch Into How Cells ‘Self-Destruct’ Maps Out Body’s Defenses Against Viruses
Researchers at Cleveland Clinic’s Center for Pathogen & Human Health Research have identified a novel mechanism for how the body defends itself against viruses using programmed cell destruction.
TREM2 Deficiency Hinders Recovery and Phagocytosis in Virus-Induced Demyelination
New research finds that TREM2 deficiency during viral-induced demyelination dysregulates expression of genes regulating phagocytic pathways and lipid metabolism, with distinct effects on recovery.
National Prostate Cancer Trial Testing Therapy Based on Cleveland Clinic Molecular Discovery
A new prostate cancer therapy in clinical trials could treat patients resistant to treatment through targeting the disease on a molecular level, based on Cleveland Clinic research.
Deep Learning Framework Unveiled for Identifying Risk Genes and Drug Targets in Alzheimer’s Disease
Application of the novel framework has identified the dyslipidemia medication gemfibrozil as a candidate drug to reduce Alzheimer’s disease risk.
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Transcriptomics-Based Study Suggests Metformin Is Repurposable for Atrial Fibrillation
A broad research effort involving network-medicine methodologies and pharmacoepidemiologic analysis has pinpointed the diabetes medication metformin as a leading antiarrhythmic candidate drug.
Adjustable Soft Robotic Sleeve Mimics Complex Hemodynamics of Aortic Stenosis
A novel soft robotic device designed to fit around the ascending aorta promises to enable high-fidelity simulation of the hemodynamics and biomechanics of aortic stenosis and congenital valve disease.
Big Patient Data Analyses Pinpoint Telmisartan as a Candidate Drug for Alzheimer’s in Black Adults
A combination of pharmacoepidemiologic studies and Mendelian randomization genetic analysis revealed preferential protection in Black but not white individuals. The findings support ongoing studies of telmisartan for Alzheimer’s, particularly in racially diverse cohorts.
Translating Genomics to Therapeutics for Atrial Fibrillation
A multifront Cleveland Clinic research project aims to use $14 million in NIH funding to identify mechanisms and targets underlying AF that may lead to personalized therapies.
How We’re Bringing the Power of Quantum Computing to Medical Research
Cleveland Clinic has been selected as a founding partner and the leading healthcare system in a new initiative meant to spur collaboration and innovation in the quantum computing industry. Quantum computers have the potential to advance medical research.
Where We’re Headed with Vaccine Research: A Conversation with Ted Ross, PhD
The renowned virologist, who is Cleveland Clinic’s new Global Director of Vaccine Development, discusses his plans and priorities for the research post.