A leading brain tumor researcher explains how the transfer of mitochondria from astrocytes may fuel glioblastoma growth.Read More
Using a multifaceted approach, Cleveland Clinic researchers have discovered molecular pathways that illuminate hyperammonemia’s role in the pathogenesis of sarcopenia, laying the groundwork for future therapies.
Cleveland Clinic teams with PDGx to harness the diagnostic power of liquid biopsy and increase the use of precision diagnostics within the cancer care continuum.
Treatment of preclinical models of glioblastoma with a BACE1 inhibitor reprogrammed tumor-promoting macrophages into tumor-suppressing macrophages, destroying tumor cells in the process.
New research shows that immune checkpoint inhibitors can enhance cancer-associated thrombosis in murine models of colon carcinoma.
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A large insurance database analysis has found a 69% relative risk reduction for Alzheimer’s development over six years, prompting mechanistic and phase 2 randomized studies.
Dietary nitrate — found in green leafy vegetables and other healthy foods — appears to inhibit platelet activation in women while increasing it in men, suggests a hypothesis-generating study.
New research shows that the sustained expression of YES1, a member of the Src family of protein tyrosine kinases, plays an important role in the growth, viability and genomic stability of triple-negative breast cancer cells.
Our radiation oncologists have compiled a list of abstracts recently presented at the annual meeting of the American Society for Radiation Oncology that they consider to be the most intriguing, clinically relevant and transformative.
Bela Anand-Apte, MBBS, PhD, MBA, new Chair of Ophthalmic Research at Cleveland Clinic, explains her department’s focus and basic science’s impact on the future of eye care.
Hydrogen sulfide signaling emerged as a possible glioblastoma tumor suppressor that is highly sensitive to dysregulation by dietary fat. The findings suggest a potential role for dietary interventions that boost hydrogen sulfide bioavailability.