The location of initial flares and uric acid deposits of gout is frequently in the extremities.
Read MoreMultidisciplinary Team Facilitates Timely Approach to Central Nervous System Vasculitis
Few clinicians are highly experienced with central nervous system vasculitis. Having a diverse team of experts who are familiar this disease and its mimics helps ensure an accurate diagnosis and workup
Use a Conventional Maintenance Agent with Rituximab in Granulomatosis with Polyangiitis
Study findings support the addition of a conventional maintenance agent, in the absence of contraindications, with rituximab to reduce the risk of relapse in granulomatosis with polyangiitis patients.
Managing Primary Immunodeficiencies: A Case Study in Complexity
Patients with common variable immunodeficiency are at risk for multiple complications and require continued monitoring for infections, granulomatous disease of the lungs, autoimmune disorders, lymphoma, malabsorption and more.
Pharmacologic Intervention Often Needed in Scleroderma-Associated Severe Digital Ischemia
Scleroderma-associated critical digital ischemia requires meticulous management. Pharmacologic or even surgical interventions may be warranted.
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In Search of a Link Among Aortitis Subclasses
Giant cell arteritis, Takayasu’s arteritis and isolated aortitis have been seen as separate diseases distinguished by age at onset and pattern of vessel involvement, but they may be more similar than previously known.
Investigation of Persistent Knee Pain and Swelling Leads to Uncommon Diagnosis
Case study: A 73-year-old woman who presented to Cleveland Clinic with persistent left knee pain and swelling is found to have non-Hodgkin lymphoma of the synovium.
Continue Maintenance Therapy for GPA (Wegener’s) at Least 36 Months
GPA (Wegener’s) characteristically has a relapsing course, and studies support continuing maintenance medications for at least 36 months.
Assessing Cardiovascular Disease Risk in Psoriatic Arthritis Patients
Carotid ultrasound is a pragmatic way to assess cardiac risk in patients with psoriatic arthritis and identify those who would benefit from early interventions
Newly Described Disease Entity: NOD2-associated Autoinflammatory Disease
Newly described entity NAID involves multiple organs. All patients to date have been white, and there is a slight female predominance. Common manifestations include flu-like symptoms, weight loss and fatigue.
Is Giant Cell Arteritis Related to Takayasu’s Arteritis?
Giant cell arteritis and Takayasu’s arteritis may not be separate diseases but rather skewed phenotypes of a single disease, influenced by genetics, age-related structural changes, immunologic senescence and environment.