Two new studies show that oral anticoagulants and prescreening for blood clots before starting cancer treatment may help prevent blood clots in high-risk cancer patients.
Researchers Receive $4.7M NIH Grant to Prevent Cancer-Associated Thrombosis
The five-year grant, led by Keith McCrae, MD, and Alok Khorana, MD, supports the creation of a new risk assessment tool to better predict which cancer patients will develop treatment-related thrombosis.
The Khorana Score 10 Years Later
Since Alok Khorana, MD, introduced this tool a decade ago, it has been validated multiple times in different countries and incorporated into a number of society guidelines.
Cancer Patients with VTE Treated in ED Face Higher Mortality Risks
Cleveland Clinic researchers recently found higher costs and death rates among cancer patients who go to the emergency department due to venous thromboembolism. They recommend prevention and/or early detection.
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Largest Biomarker Study for Cancer-Related Blood Clots Finds Circulating Tissue Factor Significant
A Cleveland Clinic-led study found that higher levels of circulating tissue factor serve as a biomarker for recurrent venous thromboembolism — a common, underestimated problem for cancer patients.
Time to Treat is Increasing, Associated with Worsened Survival
Cleveland Clinic researchers reviewed 3.7 million patient records to learn if time to treat makes a difference in mortality.
Study Identifies Predictors of Bleeding in Hospitalized Cancer Patients
Cleveland Clinic researchers identified risk factors predictive of bleeding events among hospitalized cancer patients. Findings may help optimize appropriateness of thromboprophylaxis.
New Pancreatic Cancer Treatment Guidelines Should Improve Care
The diagnosis and treatment of pancreatic cancer remains challenging, with no screening programs and relatively little progress in improving survival rates. In an effort to standardize care and address knowledge gaps, the American Society of Clinical Oncology has issued new treatment guidelines for potentially curable, locally advanced and metastatic pancreatic cancer. Cleveland Clinic Cancer Center oncologists helped lead the effort.
Doing the Right Thing for Patients with Unprovoked VTE
After an episode of venous thromboembolism without clear provocation, it’s reasonable to suspect undiagnosed cancer as an underlying factor. But how thoroughly (and expensively) should physicians search for occult underlying malignancy? A Cleveland Clinic expert weighs in on new research findings.
Why Value-Based Cancer Care Can’t Wait
Cleveland Clinic Cancer Center leaders Brian J. Bolwell, MD, and Alok Khorana, MD, say it’s time for the oncology community to embrace patient-centered value measures and improvements.