Diabetes management is often complicated with comorbidities, such as cardiovascular disease, obesity, hypoglycemia and out-of-pocket medication cost. In this article, endocrinologist Vinni Makin, MD, reviews the literature and shares best practices for diabetes management.
Read MoreBotulinum Toxin Injections Are Bringing Relief for Intractable Pediatric Migraine
More than three-quarters of children with intractable migraine who try the therapy have obtained relief and come back every three months for another round. We share learnings from our experience to date.
Higher Risk of Low Bone Mineral Density and Fractures in Survivors of Childhood Hematologic Cancers
Survivors of childhood leukemia and lymphoma are at an increased risk of reduced bone mineral density. In this article, pediatric hematologist-oncologists discuss a recent study that identifies risks associated with reduced bone density in this population.
Lenalidomide/Monoclonal Antibody Combination Superior to PI3K Inhibitor Monotherapy as First Novel Agent in Relapsed Follicular Lymphoma
Patients with relapsed follicular lymphoma who receive lenalidomide and a monoclonal antibody have better outcomes compared to those treated with PI3K inhibitors, according to data presented at the 2019 American Society of Hematology annual meeting.
Findings Suggest CAR T-Cell Therapy is Highly Effective for Relapsed/Refractory Mantle Cell Lymphoma
Relapsed/refractory mantle cell lymphoma patients significantly benefited from CAR T-cell therapy, with durable complete responses and manageable adverse events, according to new findings from the ZUMA-2 trial.
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Treatment for Myelofibrosis-Associated Anemia on the Horizon
The first-in-class erythroid maturation agent luspatercept shows significant clinical activity in patients with myelofibrosis-associated anemia, according to the interim results of a phase 2 study.
A New Era of IBD Care
Cleveland Clinic’s enterprise-wide inflammatory bowel disease (IBD) program has entered a new era, combining novel medical and surgical therapies with pioneering research.
Studies’ Results Support Liberalization of Some Eligibility Criteria for Acute Myeloid Leukemia Clinical Trials
Two related Cleveland Clinic studies examining acute myeloid leukemia outcomes in various patient populations bolster the case for easing some restrictions on clinical trial enrollment, which could increase access for patients who potentially could benefit and produc less racially biased, more generalizable results.
Performing Hemispherectomy in Adulthood Doesn’t Compromise Seizure Freedom Rates
Long-term freedom from seizures and functional outcomes for adults following hemispherectomy are similar to those in patients undergoing the surgery in infancy or childhood, a 20-year study suggests.
7T MRI Adds Critical Information for Epilepsy Presurgical Evaluation
The largest study of 7T MRI in this setting finds that it revealed subtle focal cortical dysplasia in nearly half of patients with no detectable lesions on 3T MRI. Plus, resection of these lesions was highly associated with seizure freedom.