Locations:
Search IconSearch
April 4, 2022/Neurosciences/Podcast

Epilepsy Surgery: An Underused Treatment Option (Podcast)

Surgery can be a game changer when medications fail to control seizures

Epilepsy surgery is a viable treatment option when more than two appropriately prescribed medications fail to control seizures. However, it remains significantly underutilized.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

“Every patient is a surgical candidate once they fail a couple of medicines,” says William Bingaman, MD, Vice Chair of Cleveland Clinic’s Neurological Institute and Director of the Epilepsy Surgery Program in its Charles Shor Epilepsy Center. “The trick then is just to be able to tell patients what their chances are to become seizure free so they can drive, work or even just take a bath or shower by themselves without fear of drowning.”

In the latest episode of Cleveland Clinic’s Neuro Pathways podcast, Dr. Bingaman discusses the state of epilepsy surgery and its value in the care of individuals with uncontrolled epilepsy. He touches on:

  • The evolution of epilepsy surgery
  • Factors that contribute to low surgical referrals
  • Types of epilepsy procedures, including resection, palliative surgery and laser ablation
  • The role of magnetoencephalography and imaging modalities
  • The future of epilepsy surgery and drug delivery into the brain

Click the podcast player above to listen to the episode now, or read on for a short edited excerpt. Check out more Neuro Pathways episodes at clevelandclinic.org/neuropodcast or wherever you get your podcasts.

This activity has been approved for AMA PRA Category 1 Credit™. After listening to the podcast, you can claim your credit here.

Excerpt from the episode

Podcast host Glen Stevens, DO, PhD: The great news is that there are a lot of epilepsy drugs out there now, versus when you and I started to practice. In some ways, the bad news is that there are a lot of epilepsy drugs out there. It becomes easy for neurologists to say, “Well, let’s try this new drug,” doesn’t it?

Advertisement

Dr. Bingaman: It could take 10 or 15 years probably to go through all the drugs on a fair trial. It reminds me of a patient I saw last year who came up from central Ohio. She was in her late 60s, and she had hippocampal sclerosis, the most common adult epilepsy we see and also the type that responds most successfully to epilepsy surgery. She had a febrile convulsion as a baby. At 15, she started having seizures and had been seizing for 50 years.

She and her husband were sitting in my clinic and we were talking about temporal lobectomy, which we typically don’t do on people in their 60s. Occasionally we do, but it’s rare. So I said, “Gosh, you’ve had seizures for 50-some years. Why now? Why are you here now?” And she looked at me and said, “Well, I didn’t know surgery was an option.” … That’s unfortunately something we still see, and 50 years of uncontrolled epilepsy can really do a number on someone.

Advertisement

Related Articles

stylized illustration of a chemical compound made up of connected multicolor spheres

What’s the Outlook for BTK Inhibitors in Progressive Multiple Sclerosis?

Despite safety concerns and mixed trial results, experts see potential for this indication

Illustration of two football helmets butting into each other with an inflamed brain underneath one helmet

A Call to Find and Validate Diagnostic Biomarkers for Chronic Traumatic Encephalopathy

Experts endorse a push to improve prevention and treatment following repetitive head injury

dr. charles bernick against decorative background with podcast icon overlay
May 18, 2026/Neurosciences/Podcast

Recognizing and Managing Alzheimer’s Disease in People With Down Syndrome (Podcast)

A population with very high lifetime risk presents care challenges and pathophysiologic insights

Dr. Dylan Wint talking to a patient in a medical office

Alzheimer’s Disease Nears an Inflection Point in Diagnosis and Care

Two Cleveland Clinic neurologists review biomarker advances, targeted therapies and unresolved clinical challenges

brain illustration covered with dots and letter labels atop a ruled grid
May 12, 2026/Neurosciences/Epilepsy

Automated Framework Matches Expert Precision in Mapping Seizure Evolution

Data-driven segmentation approach shows promise for seizure characterization with utility for clinical decision making

Illustration of  a woman's head and a glow where the brain would be

New WAM Grants Support Research on Gut-Brain Interactions, Menopause and Sarcopenia

Alzheimer’s studies delve into preventing and modifying the disease’s trajectory and impact

illustration of lumbar spine with inset showing area of defect
April 23, 2026/Neurosciences/Spine Care

Two-Level Fusion Eases Complex Bertolotti Syndrome Disability

Study finds broadly similar outcomes between MIS and open surgical approaches

Woman helping older woman as she walks with a cane

New Model Performs Well Predicting Parkinson’s Sentinel Falls

System uses clinical data routinely collected at clinical visits

Ad