Locations:
Search IconSearch
March 2, 2022/Neurosciences/Podcast

Neurostimulation for Treatment of Obstructive Sleep Apnea (Podcast)

An in-depth look at this alternative for patients who cannot tolerate PAP therapy

While there are comprehensive treatment options for obstructive sleep apnea (OSA), the disorder is underrecognized and underdiagnosed, says Jessica Vensel Rundo, MD, MS, Director of the Sleep Neuromodulation Program in Cleveland Clinic’s Sleep Disorders Center.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

“About 25% to 50% of males and 10% to 25% of females have some degree of obstructive sleep apnea,” says Dr. Vensel Rundo. “That translates to many millions of Americans.”

In 2014, a new category of surgical therapy became available to help this population when the FDA approved the first neurostimulation device to treat OSA. In the latest episode of Cleveland Clinic’s Neuro Pathways podcast, Dr. Vensel Rundo discusses OSA and hypoglossal nerve stimulation, providing insight on the following:

  • Positive airway pressure (PAP) therapy as the first line of treatment for OSA
  • Screening criteria and ideal candidates for airway neurostimulation
  • Implantation and function of the transcutaneous electrical stimulator
  • Patient outcomes following neurostimulation
  • Potential future devices, including a bilateral hypoglossal nerve stimulator and a continuous negative expiratory pressure device

Click the podcast player above to listen to the episode now, or read on for a short edited excerpt. Check out more Neuro Pathways episodes at clevelandclinic.org/neuropodcast or wherever you get your podcasts.

This activity has been approved for AMA PRA Category 1 Credit™. After listening to the podcast, you can claim your credit here.

Excerpt from the episode

Podcast host Glen Stevens, DO, PhD: Would you recommend that anybody who is thinking about airway neurostimulation see a sleep specialist, or can they go to their general neurologist for this?

Dr. Vensel Rundo: I think it usually is most helpful if they can be referred to a sleep specialist, just to discuss in more detail what their issues are with PAP therapy and what other potential options there might be in addition to hypoglossal nerve stimulation.

Advertisement

Also, we see a number of patients who are intolerant to PAP therapy or just struggle with whatever their treatment option is for sleep apnea. Other patients may also struggle because they have additional sleep disorders like insomnia, restless legs syndrome or circadian rhythm disorders. In these cases, a sleep specialist is best equipped to assess why these patients may have difficulties adhering to their current treatment option and to determine whether other sleep disorders may be contributing to these difficulties.

Advertisement

Related Articles

Two-dimensional scatter plot of peak T1 versus T2 times from pre-extended lumbar drainage MRI

MR Fingerprinting Predicts Shunt Efficacy in NPH

Study tests potential for a more accurate treatment predictor

person going into a Gamma Knife machine for radiotherapy
March 25, 2026/Neurosciences/Brain Tumor

Predicting Response to Stereotactic Radiosurgery for Recurrent Glioblastoma

Study uses molecular and clinical stratification to help guide patient selection

illustration of human brain with rumor at top right
March 23, 2026/Neurosciences/Brain Tumor

Adding Eflornithine to Lomustine Extends Survival in Recurrent IDH-Mutant Grade 3 Astrocytoma

Phase 3 STELLAR trial underscores role of molecular stratification in glioma care

brain MRI taken from the back of the head
March 20, 2026/Neurosciences/Epilepsy

Unmasking the ‘Tethered’ Temporal Lobe: New MRI Metrics Improve Detection of Encephaloceles in Refractory Epilepsy

Early identification of temporal encephaloceles can improve surgical decision-making

brain scan with white lesion on right side

ARISE II Recommendations Chart a Course for Advancing Intracranial Hemorrhage Care

Academia, industry and government leaders develop consensus priorities

two brain scans side by side with a yellow circle on the left scan
March 13, 2026/Neurosciences/Epilepsy

SEEG Linked With More Complete Resection and Greater Seizure Freedom in MOGHE Subtype of Epilepsy

Insights from one of the first studies of invasive monitoring in the rare form of focal cortical dysplasia

histopathology image with pink background and arrow pointing to round cell

New Insights on α-Synuclein Pathology and Clinical Phenotypes in Dementia With Lewy Bodies

The disease’s neuropathologic heterogeneity holds clues to refining diagnosis and prognosis

MRI of the brain against black background

Advanced Neuroimaging and Clinical Perseverance Make Sense of a 68-Year-Old’s Progressive Symptoms

A case study in pairing imaging acumen with subspecialty expertise to yield answers and symptom relief

Ad