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Basic & Translational Science

Karnik lab

Pro-Collagen Pathway Regulated by MAS and CTGF May Promote Heart Failure

Study of cardiac tissue samples suggests pharmacotherapy target

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Reversal of Alzheimer’s in Mouse Model Boosts BACE1 Inhibitors’ Prospects in Humans

Most substantial reversal of amyloid deposition in an animal study to date

Fat Cells from adipose tissue. adipocytes. inside human organism

New Signaling Pathway May be Key to Preventing Diet-Related Obesity

Researchers uncover pathway that suppresses fat accumulation

Breast cancer cell

How Cancer Stem Cells Drive Triple-Negative Breast Cancer

Discovery of mechanistic links may lead to new therapies

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Can Stem Cells ‘Stem’ the Use of Opioids? Study Shows Great Promise

Awaiting FDA approval and funding to begin clinical trials

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Scientists Uncover the Biochemical Key to a Devastating Disease

Answer lies in a single mutation in a key protein

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