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Basic & Translational Science

Karnik lab

Pro-Collagen Pathway Regulated by MAS and CTGF May Promote Heart Failure

Study of cardiac tissue samples suggests pharmacotherapy target

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Reversal of Alzheimer’s in Mouse Model Boosts BACE1 Inhibitors’ Prospects in Humans

Most substantial reversal of amyloid deposition in an animal study to date

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Fat Cells from adipose tissue. adipocytes. inside human organism

New Signaling Pathway May be Key to Preventing Diet-Related Obesity

Researchers uncover pathway that suppresses fat accumulation

Breast cancer cell

How Cancer Stem Cells Drive Triple-Negative Breast Cancer

Discovery of mechanistic links may lead to new therapies

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Can Stem Cells ‘Stem’ the Use of Opioids? Study Shows Great Promise

Awaiting FDA approval and funding to begin clinical trials

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Scientists Uncover the Biochemical Key to a Devastating Disease

Answer lies in a single mutation in a key protein

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Found: Protein that Keeps Mice Lean on a High-Fat Diet

Inhibiting the gene could slow the obesity epidemic

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