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Basic & Translational Science

Medical graphic depicting CD55 movement to cell nucleus

Nuclear CD55 Fuels Platinum Resistance in Ovarian Cancer

Researchers identify potential path to retaining chemo sensitivity

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September 12, 2024/Neurosciences/Research

Preclinical Imaging Research Aims to Help Refine Deep Brain Stimulation for Stroke Recovery

$3.2 million grant will fund use of calcium-based imaging to record neuronal activity in ischemia model

gut microbes in the human intestine

Gut Microbial TMAO Pathway Associated With Incident Heart Failure

Metabolites from animal product substrates implicated in heart failure development in community cohorts

chemical structure of erythritol drawn in a teaspoon

Evidence Mounts That Sugar Substitute Erythritol Raises Cardiovascular Risk

Study authors urge reevaluation of the sweetener’s safety designation by food regulators

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gut-brain axis

Assessing Alzheimer’s Disease Drug Targets Along the Gut-Brain Axis

Pairing machine learning with multi-omics revealed potential therapeutic targets

nutrition label of product containing xylitol

Another Sugar Substitute, Xylitol, Is Linked to Heightened Cardiovascular Risk

Studies reveal increased cardiac events, enhanced platelet reactivity and thrombotic potential

deep brain stimulation of dentate nucleus

Deep Brain Stimulation After Stroke: What Underlies Improved Motor Function?

EDEN analysis investigates electrophysiological changes after continuous dentate nucleus stimulation

brain puzzle with piece missing and female symbol

Latest WAM Grant Recipients Take on Alzheimer’s Disease in Women Across Multiple Fronts

Awards fund research on oxidative targets, immunometabolism, spatial navigation testing and more

gut microbes in intestine

Cleveland Clinic, Tufts University Research Ties Gut Microbial TMAO Pathway to Chronic Kidney Disease

Large-scale joint study links elevated TMAO blood levels and chronic kidney disease risk over time

patient in ICU

Cleveland Clinic and Purdue Seek to Revolutionize Intensive Care Through AI

Investigators are developing a deep learning model to predict health outcomes in ICUs.

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