While dyspnea is a common complaint among patients, its cause can be difficult to diagnose and manage. A Cleveland Clinic pulmonologist describes dyspnea that is linked to a chronically low preload state.
A new study shows serum chloride can help predict mortality in patients with pulmonary arterial hypertension. Lower level at six-month postdiagnosis is linked to larger left atrium and higher pulmonary wedge pressure.
These findings suggest that the RAP/PAWP ratio is a more specific marker of right heart dysfunction than RAP or any other traditional hemodynamic variable alone.
Hypoxemia at rest or during activities is associated with worse prognosis in pulmonary conditions such as COPD and interstitial lung diseases. This study adds IPAH and HPAH to the list.
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Uncovering the nature, extent and significance of systemic vascular involvement in pulmonary arterial hypertension (PAH) may unlock a correlation to disease severity or response to therapy, leading to future treatment options