Microglia can be both protective and damaging to the brain. A neuroscientist explains how his lab is working to characterize responses and pathways that alter key microglial interactions in health versus disease.
The elusive ability to penetrate the blood-brain barrier may have gotten easier thanks to a new device developed at Cleveland Clinic. The lead developer shares insights.
Cleveland Clinic researchers have found evidence that the circulating astrocytic protein S100B might be useful as a biomarker for blood-brain barrier breakdown triggered by childhood trauma and abuse. If further validated, a serum test for S100B could help clinicians assess the severity of emotional injury and the need for intervention.