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Research

Medical illustration of microglia
December 10, 2024/Genomic Medicine/Research

Network-based analyses uncover how harmful microglia form in Alzheimer’s disease

Study identifies Ketorolac as a potential repurposable drug

Illustration of a brain
November 6, 2024/Neurosciences/Research

Genomic Analysis Finds Connections Between Transposable Elements and Alzheimer's Disease

Understanding TE involvement is a key to developing new treatments

Man on an exercise bicycle
October 29, 2024/Neurosciences/Research

New Parkinson’s Trial Focuses on Interplay Between Exercise and Genetics

Study aims to inform an enhanced approach to exercise as medicine

researcher in dark laboratory
September 12, 2024/Neurosciences/Research

Preclinical Imaging Research Aims to Help Refine Deep Brain Stimulation for Stroke Recovery

$3.2 million grant will fund use of calcium-based imaging to record neuronal activity in ischemia model

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neurons, axons and synapses in the brain
September 5, 2024/Neurosciences/Research

A Case Study in Neurotherapeutic Clinical Trial Design and Conduct

New phase 1 trial showcases Neurological Institute’s interdisciplinary study capabilities

Illustration of brain activity
August 28, 2024/Neurosciences/Research

Brain Research Finds Notable Differences in Changes Based on Sex and Race

Chronic stress, asymptomatic disease affect different brains differently

anatomic spine with vectors displayed

Novel ‘Global Shear Vector’ Metric Provides New Insights Into Spinal Alignment

Tool correlates well with sagittal vertical axis and quality-of-life measures

illustration of an alzheimer brain and a packet of sildenafil pills
March 11, 2024/Neurosciences/Research

Sildenafil as an Alzheimer’s Candidate Drug: Further Support From Insurance Database and Mechanistic Studies

Real-world claims data and tissue culture studies set the stage for randomized clinical testing

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Multi-Ancestry Genetic Study of Parkinson’s Disease Identifies New Risk Genes in Pursuit of Novel Treatment Targets

International collaboration is most genetically diverse study of the disease to date

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Noninvasive Technology Enhances Ability to Map Brain Activity to Track Behavior Change

Preclinical work promises large-scale data with minimal bias to inform development of clinical tests

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