Clinical trials of TRIKAFTA demonstrated robust improvement in pulmonary function in patients with cystic fibrosis. In this article, pediatric pulmonologist Nathan Kraynack, MD, shares his early experience with the new, game-changing regimen.
In the largest study of its kind, Cleveland Clinic physicians found that the survival rate for patients with cystic fibrosis who undergo mechanical ventilation is much higher than previously understood.
With drug-resistant bacterial infections on the rise, experts are reexamining a century-old therapy as a possible intervention. Despite some limitations, experts say it’s time to define its utility in difficult-to-treat infections. A Cleveland Clinic infectious disease physician shares a recent case study.
Inclusion of clinical data points could improve access to lung transplant for some cystic fibrosis and COPD patients.
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Guidelines for referral and transplantation timing for patients with CF are lacking, so Cleveland Clinic has formed a CF lung transplant transition collaborative that includes Cleveland Clinic and referring providers, as well as patients, to address these and other issues.
Persistent MRSA in patients with CF is not easy to prevent or treat, but stringent infection control practices can reduce transmission and optimize outcomes.
MRSA is an especially ubiquitous pathogen in patients with CF. Risk factors must be evaluated, and strict infection control practices must be in place to prevent MRSA, minimize transmission and optimize CF patient outcomes.
Our multidisciplinary team treats local patients as well as CF patients from all over the world with difficult-to-treat infections.
Recent therapeutic advances that target the basic genetic defect in cystic fibrosis is proving to be a game changer in treating adult CF.
The director of Cleveland Clinic Children’s cystic fibrosis program opines on the merits and pitfalls of newborn screening, when to refer and the benefits of teaming with adult-care specialists.