A 17-year-old patient with a homozygous mutation in MYBPC3, who underwent orthotopic heart transplantation, presents with persistent cough. Work-up leads to finding of asymptomatic aortic dissection. In this case study, pediatric cardiologist Kenneth Zahka, MD, points to the need for pediatric-specific guidelines for intervention in post-orthotopic heart transplant patients with known aortic dilatation.
First Successful Use of Biventricular Impella Pumps as a Bridge to Heart Transplant
This unprecedented case report shows that, in the right patients, biventricular support with Impella devices can minimize the risk of complications and reduce transplant recovery time.
Case Report: Heart-Liver Transplant in a Child with Mitochondrial Disease
In this complex case, the immediate complications of what would later be confirmed as mitochondrial disease required Cleveland Clinic Children’s specialists to perform not one, but two, transplants that saved a young patient’s life.
Time to Include eGFR and Serum Albumin Among Heart Allocation Criteria?
All but two of the variables most predictive of who’s likely to die on the heart transplant waitlist are included in the allocation system for donor hearts, finds an analysis of the SRTR national database.
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Continuously Updated Model Promises to Refine Heart Transplant Waitlist Mortality Estimates
Risk is dynamic for patients on the heart transplant waitlist. We’ve developed a decision aid for risk estimation that reflects that fact, with the hope of ultimately reducing waitlist deaths.
Research to Predict Pre- and Post-Transplant Survival in Heart Failure Lands $2.8M NIH Grant
The funding will support a three-pronged initiative using machine learning and other methods to identify factors behind survival disparities to improve survival and minimize organ wastage.