A 17-year-old patient with a homozygous mutation in MYBPC3, who underwent orthotopic heart transplantation, presents with persistent cough. Work-up leads to finding of asymptomatic aortic dissection. In this case study, pediatric cardiologist Kenneth Zahka, MD, points to the need for pediatric-specific guidelines for intervention in post-orthotopic heart transplant patients with known aortic dilatation.
This unprecedented case report shows that, in the right patients, biventricular support with Impella devices can minimize the risk of complications and reduce transplant recovery time.
All but two of the variables most predictive of who’s likely to die on the heart transplant waitlist are included in the allocation system for donor hearts, finds an analysis of the SRTR national database.
Risk is dynamic for patients on the heart transplant waitlist. We’ve developed a decision aid for risk estimation that reflects that fact, with the hope of ultimately reducing waitlist deaths.
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The funding will support a three-pronged initiative using machine learning and other methods to identify factors behind survival disparities to improve survival and minimize organ wastage.