TLR4: The Key to Cancer Stem Cell Evasion of Immune Suppression?

Through a side-by-side comparison of CSC and non-CSC reactions in specific TLR cultures, Dr. Lathia and his teams found that CSCs in GB have adapted to express a lower level of the innate TLR4. These diminished TLR4 levels allow the CSCs to persist and multiply, repopulating a tumor in a hostile microenvironment.

Advertising Policy

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services Policy