New Insights on Post-Transplant Survival after Acute-on-Chronic Liver Failure

Patients with acute-on-chronic liver failure, even those with advanced-grade disease and circulatory failure requiring multiple vasopressors, can achieve one-year survival rates exceeding 80% following liver transplantation, a large North American multicenter study including Cleveland Clinic researchers has found. But the presence of portal vein thrombosis in patients with the most severe ACLF is cause for caution regarding transplantation.