Locations:
Search IconSearch
February 16, 2022/Neurosciences/Podcast

Understanding the Role and Future of Peripheral Nerve Neurosurgery (Podcast)

Growing subspecialty offers options for patients with a host of nerve injuries and diseases

Peripheral nerve neurosurgery is a subspecialty that’s little understood. However, it can be game-changing for people with acute nerve injuries, entrapment neuropathies, benign nerve tumors and other nerve disorders.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

“The best part of my job is working directly with patients and helping them restore function and helping take away pain, which for some of my patients really changes their lives,” says Megan Jack, MD, PhD, a peripheral nerve neurosurgeon and researcher in Cleveland Clinic’s Neuromuscular Center. “It gets them back to work. It gets them back to enjoying the life they had.”

In the most recent episode of Cleveland Clinic’s Neuro Pathways podcast, Dr. Jack talks about the value of peripheral nerve neurosurgery within the nerve injury treatment landscape. She delves into:

  • Conditions that are best suited to peripheral nerve neurosurgery
  • The importance of a multidisciplinary approach to treating patients with nerve injuries
  • The slow pace of nerve regeneration and potential surgical options to speed it up
  • A move toward surgeries that restore sensation as well as improve motor skills
  • Research into new peripheral nerve surgeries, medications and other treatments

Click the podcast player above to listen to the 21-minute episode now, or read on for a short edited excerpt. Check out more Neuro Pathways episodes at clevelandclinic.org/neuropodcast or wherever you get your podcasts.

This activity has been approved for AMA PRA Category 1 Credit™. After listening to the podcast, you can claim your credit here.

Excerpt from the episode

Podcast host Glen Stevens, DO, PhD: This is a loaded question and has a lot of caveats, but who do we intervene on?

Megan Jack, MD: I think early referral to a peripheral nerve neurosurgeon [is important]. One of the unfortunate things that I’ve seen throughout the field is that nerves take a long time to recover. So we watch our patients very closely. But as that continues, it moves them more and more toward being outside that surgical window.

Advertisement

Typically, laceration is something we like to repair within three days, but that’s pretty rare. For most patients, we like to intervene anywhere from three to six months if we haven’t seen recovery either clinically or on an EMG or functionally. And so for those patients, it’s sort of a race against time to where you’re giving them enough time to recover on their own if they’re going to recover, but you don’t want to go so far that the de-innervation changes that occur in the muscle — those more permanent losses of muscle — makes it so you can’t functionally get back any of that muscle weakness that’s occurred even after surgery.

It’s sort of threading the appropriate needle to intervene, when necessary, but doing it in the appropriate time. I always say, refer your patients early to us. We like to get a good exam early on. That way we’re able to follow the patient to determine if they are recovering properly. Take Parsonage-Turner syndrome, for example. Almost 80% of those patients get better on their own, but it’s the 20% of patients who don’t for whom we want to make sure we intervene early enough that we can actually change their outcomes.

Advertisement

Related Articles

scan of a human brain

Study Links ANNA1/Hu-IgG Paraneoplastic Neurological Syndromes With Longer Cancer Survival

Findings may have implications for understanding the disorders’ pathophysiology

portait of Dr. Jay Alberts against decorative background with podcast icon overlay
July 16, 2026/Neurosciences/Podcast

Reshaping Research With Our New Neurological Assessment Center (Podcast)

Routine capture of standardized neuroperformance data may expand and refine investigations

woman looking concerned as she listens to a doctor speak to her

Study Offers First Characterization of Patients With Nonspecific Presentations of Multiple Sclerosis

Nearly one-fifth of such cases fulfill 2024 McDonald criteria based on biomarkers

gamma knife machine

Stereotactic Radiosurgery Shows Strong Local Control in SCLC Brain Metastases

Adequate dosing may improve outcomes in well-selected patients, large Cleveland Clinic series suggests

portrait of Dr. Robert Bermel against a decorative backdrop with podcast icon overlay
July 2, 2026/Neurosciences/Podcast

Inside Our New Neurological Assessment Center (Podcast)

Reimagining the outpatient neurological visit with routine capture of neuroperformance data

woman in white medical coat typing on a laptop in lab setting
June 30, 2026/Neurosciences/Epilepsy

Online Tool Makes It Easier to Share and Analyze Data on Epilepsy-Related Cognitive Disorders

Free portal helps researchers classify and share data using the IC-CoDE framework

woman in wheelchair being wheeled into or out of an elevator

Key Rural-Urban Differences Revealed in U.S. Post-Acute Stroke Care

Large study shows rural patients are less apt to be discharged to inpatient rehab, hampering outcomes

portrait of Dr. Jeffrey Cohen against decorative background with podcast icon overlay
June 16, 2026/Neurosciences/Podcast

The Potential of CAR T-Cell Therapy in Multiple Sclerosis (Podcast)

Updates on this fast-evolving therapeutic landscape from a leading trialist

Ad