Actively Enrolling Clinical Trials

Studies open to your qualifying GI patients

Cleveland Clinic

Ohio Colorectal Cancer Prevention Initiative: Universal Screening for Lynch Syndrome
Matthew Kalady, MD

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PILLAR III A Randomized, Controlled, Parallel, Multicenter Study Assessing Perfusion Outcomes with PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection
Emre Gorgun, MD

Comparative Assessment of Three-dimensional vs. Conventional Laparoscopy in a Total Colectomy
Model for Ulcerative Colitis
Emre Gorgun, MD

A Randomization, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of Topical Alicaforsen
Enema in Subjects with Active, Chronic, Antibiotic Refractory Primary Idiopathic Pouchitis
Bo Shen, MD

A Phase II, Randomized, Doubleblind, Placebo-controlled Study of IMM-124E for Patients with Nonalcoholic Steatohepatitis
Arthur McCullough, MD

Novel Therapies for Moderate Alcoholic Hepatitis
Arthur McCullough, MD

Novel Therapies for Severe Alcoholic Hepatitis
Arthur McCullough, MD

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Nonalcoholic Fatty Liver Disease (NAFLD) Database
Arthur McCullough, MD

Treatment Use of Domperidone
Scott Gabbard, MD

Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease: OCEANIA
Jean-Paul Achkar, MD

Cleveland Clinic Inflammatory Bowel Disease DNA Bank
Jean-Paul Achkar, MD

Prospective Cohort of Ulcerative Colitis and Crohn’s Disease Patients Undergoing Surgery to Identify Risk
Factors for Post-Operative Infection l (PUCCINI)
Bo Shen, MD

Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients with Breast Cancer (“ICG”)
Stephen Grobmyer, MD

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A Phase III, Randomized, Doubleblind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and
Safety of ETROLIZUMAB as an Induction and Maintenance Treatment for Patients with Moderately to
Severely Active Crohn’s Disease (Protocol GA29144 “Bergamot”)
Bret Lashner, MD

A Randomized Controlled Clinical Trial of Thymoglobulin® and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation. A Multicenter Study
Bijan Eghtesad, MD

A Phase I Pilot Study to Assess Safety and Feasibility of Normothermic Machine Preservation in Human Liver
Transplantation/IND Holder
Cristiano Quintini, MD

Limited Access Protocol for the Use of Oral Cisapride in the Treatment of Refractory Gastroesophageal Reflux
Disease and other Gastrointestinal Motility Disorders
Michael Cline, DO

A Prospective Randomized Trial of Biologic Mesh vs. Synthetic Mesh for the Repair of Complex Ventral Hernias
Michael Rosen, MD

A Randomized, Open-label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD® in Subjects with Alcohol-induced Liver Decompensation (AILD)
Talal Adhami, MD

Cleveland Clinic Florida

Fluorescent Cholangiogram: A Comparative Analysis to Conventional Cholangiography
Raul Rosenthal, MD

Management of Patients With New Ileostomies: Can a Specific Protocol Reduce the Readmission Rates?
Giovanna da Silva, MD

A Randomized, Controlled Trial to Compare the Functional Outcome and Quality of Life of Patients With
Low Rectal Cancer, Who Undergo a J Pouch or a Side-to-end Coloanal Anastomosis
Steven Wexner, MD

Laparoscopic Rectal Prolapse Surgery: An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy with Laparoscopic Resection Rectopexy
Steven Wexner, MD

Registry: Management of Patients with Cryptoglandular Horseshoe Abscess and Fistula in Cleveland
Clinic Florida
Lester Rosen, MD

Statin Polyp Prevention Trial in Patients with Resected Colon (NSABP P-5)
Bruno Bastos, MD

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Comparison Between Optical Nerve Diameter, Body Mass Index, Hypertension and Abdominal
Perimeter
Raul Rosenthal, MD

AbbVie LEGACY Registry
Nicole Palekar, MD

SECURE Registry UCB Schwarz Biosciences
Nicole Palekar, MD

Barbed Sutures a Novel Technique in the Closure of Diaphragmatic Defects
Raul Rosenthal, MD

A Randomized, Controlled, Parallel, Multicenter Study Assessing Perfusion Outcomes with PINPOINT®
Near Infrared Fluorescence Imaging in Low Anterior Resection (PILLAR III)
David Maron, MD

Functional Recovery in Elderly Patients Undergoing Open or Laparoscopic Surgery for Colorectal
Cancer? A Prospective Multicenter International Study
Fabio Potenti, MD

Jagelman Registries
Giovanna DaSilva, MD

Prospective Cohort of Ulcerative Colitis and Crohn’s Disease Patients Undergoing Surgery to Identify Risk
Factors for Post-Operative Infection I. (PUCCINI)
Nicole Palekar, MD

A Multicenter, Randomized, Double-blind Study to Compare the Efficacy and Safety of Cadazolid vs. Vancomycin in Subjects with Clostridium Difficile-Associated Diarrhea (CDAD) and Sub-study to Validate the CDAD-DaySyms (Clostridium Difficile-associated Diarrhea – Daily Symptoms) PRO in Subjects with CDAD Participating in Study AC-061A301 or AC-061A302
Alison Schneider, MD

A Randomized, Double-blinded, Placebo-controlled Trial of TU-100 in Patients Undergoing Laparoscopic
Colectomy (Protocol TU100P2T3)
Steven Wexner, MD

To learn more about any of the above studies, contact the central number for DDSI Clinical Research at 216.636.5340. For Florida, call 954.659.5861.