Locations:
Search IconSearch
December 11, 2017/Digestive/Research

New Study Proves that Dedicated Units Help Keep Cirrhotic Patients from Returning to Hospital

Special training and care reduces readmission by 33 percent

CQD_HDU_huddleround

Patients with cirrhosis represent about 150,000 hospitalizations each year, resulting in a $4 billion financial burden in the U.S. Regardless of the hospital setting, within three months of their stay, about 50 percent of cirrhotic patients are readmitted. Readmitting patients with end-stage liver disease increases the financial burden and may lead to further health complications for the patient.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Perhaps the most frustrating part of these high readmission rates is that the majority of cirrhotic patients are readmitted for preventable causes. This means that if the hospital staff had measures in place to better care for these patients during and after their stay, readmission rates could be reduced dramatically. Until recently, however, the importance of dedicated hospitalization units had been unrecognized.

At The Liver Meeting® 2017, the annual conference of the American Association for the Study of Liver Diseases (AASLD), Cleveland Clinic presented the results of ongoing efforts by the hospital’s SOLVE Continuous Improvement Project, comparing the outcomes of patients cared for in a hepatology dedicated unit (HDU) with those cared for in a general medicine unit. The study revealed for the first time that caring for cirrhotic patients in an HDU results in a 33 percent reduction in 30-day readmission rates.

Problems involving readmission

Readmission creates a variety of problems for hospitals and patients. If patients return to the hospital within 30 days, the hospital may face reimbursement penalties. Cirrhotic patients are often readmitted with infections and other health problems. If they’re readmitted with a serious infection, they may no longer qualify for a transplant either on a temporary or permanent basis. This can lead to significant quality-of-life issues, reduced patient satisfaction and poor outcomes.

Why are patients with end-stage liver disease readmitted so frequently? According to Bhavana Bhagya Rao, MD, a second-year fellow in Cleveland Clinic’s Department of Gastroenterology & Hepatology and the first author of the HDU study, “Following discharge, cirrhotic patients often have recurrence of hepatic encephalopathy (HE), a condition that can easily be prevented with the proper use of medication.” Study co-authors included Anastasia Sobtoka, RN, Carlos Romero-Marrero, MD, and William D. Carey, MD.

Advertisement

Specialized training and experience

Cleveland Clinic has been caring for cirrhotic patients in an HDU for nearly 10 years. All HDU staff members have special training and experience in managing advanced liver disease. For example, the nurses receive hands-on training in caring for cirrhotic patients, including HE care and prevention. Each day, the entire physician team, including social workers, case managers, nutritionists, physical therapists and nursing representatives, conduct a ‘huddle round’ during which they review each patient in the HDU and develop individualized care plans, including early discharge planning.

Cleveland Clinic operates a four-bed closed observation unit (COU) for cirrhotic patients as part of the HDU. These patients receive 24/7 monitoring and care from a dedicated team.

“In addition to training our staff, we’re also proactive in teaching our patients how to identify and prevent complications through diet and medication,” reveals Dr. Rao. “By educating patients, we’re empowering them to manage their own health.”

Continuously improving patient care

In 2016, Cleveland Clinic hired a full-time care coordinator to work closely with cirrhotic patients who were hospitalized in the HDU. In addition to ensuring a safe discharge, the coordinator ensures that the patient follows his or her schedule for outpatient labs and follow-up appointments. Cleveland Clinic is currently analyzing the results of this addition to the continuous improvement project and plans to present these results at the Digestive Disease Week meeting in June 2018.

Advertisement

Cleveland Clinic’s research may help leaders at other hospitals who want to reduce readmission rates, even if financial challenges prevent them from operating dedicated hepatology units. “Simply caring for cirrhotic patients in one geographic location and training nursing staff can substantially improve patient outcomes,” explains Dr. Rao. “It’s a team effort that requires organization and coordination. But the results make it all worthwhile.”

Advertisement

Related Articles

Illustration of J pouch
May 21, 2026/Digestive/Research

Ulcerative Colitis Patients with Pyoderma Gangrenosum Have Worse Outcomes with J-Pouch Surgery, Study Finds

Patients have a significantly higher risk of developing fistulas and experiencing future Crohn’s-like changes

Dr. Gorgun in operating room
May 20, 2026/Digestive/Research

Cleveland Clinic Colorectal Surgeons Develop a New Standardized Endoscopic Grading System for Rectal Cancer Response and Organ Preservation

Cleveland Clinic researchers developed an objective tool to assess response following total neoadjuvant therapy.

Patient speaking with physicians
May 11, 2026/Digestive/Research

Adherence to Lifestyle Changes Peaks One Month After Bariatric Surgery, Study Finds

Patients may benefit from booster appointments, psychological support

Dr. Aminian in OR
May 7, 2026/Digestive/Research

Metabolic Surgery May Reverse MASH Cirrhosis, Paired Biopsy Study Suggests

Research demonstrates cirrhosis regression in one-third of patients, with higher rates using alternative assessment

Dr. Regueiro speaking with patient
May 6, 2026/Digestive/Research

Patients With IBD Who Undergo Colon Cancer Surgery Have Higher Blood Clot Risk

Elevated risk persists for more than a year after surgery, plus more insights from the first study to quantify risk specifically for CRC surgery

Pharmacist filling order
May 5, 2026/Digestive/Research

Fenofibrate-UDCA Combination Therapy Safe and Effective for Primary Biliary Cholangitis

Large, retrospective study indicates improved outcomes after one and five years of treatment

Dr. Bhatt with clinician
April 28, 2026/Digestive/Innovation

Endorobotics Collaborative: A New Era in Gastrointestinal Procedures

Multidisciplinary collaboration is fueling breakthroughs in endoscopic and surgical technology

Dr. Kwan and Dr. Hashimoto performing Laparoscopic Liver Transplant Surgery
April 9, 2026/Digestive/Transplant

Transforming Liver Transplantation at Cleveland Clinic

A surge in transplants, advanced surgical techniques and multidisciplinary collaboration has helped shape and expand the Liver Transplant Program

Ad