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Novel ‘Global Shear Vector’ Metric Provides New Insights Into Spinal Alignment

Tool correlates well with sagittal vertical axis and quality-of-life measures

Assessing global shear vector (GSV) of the spine — i.e., the sum of the shear weight vectors applied on each vertebra (Figure) — can provide greater understanding of spine biomechanics, promising to one day better inform surgical evaluation for spine deformity. The GSV assessment tool, developed by a Cleveland Clinic Center for Spine Health team led by neurosurgeon Ghaith Habboub, MD, can be accessed via an online application. It can calculate GSV using a scoliosis X-ray of the spine plus patient weight.


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“This is the first spinal assessment that accounts for the contribution of forces on each vertebra, based on alignment and weight,” says Dr. Habboub, whose group has submitted a study of the GSV metric for publication. “By providing detailed information on the shear forces pushing the spine anteriorly, this metric will help us determine how to better surgically realign the spine.”

anatomic spine with local coordinate system
Figure. Anatomic spine with local coordinate system and vectors displayed on multiple vertebra. The downward red vector displays the force of weight and gravity, which are split into the shear and normal components. The vertebral slope, or pitch angle, is used when splitting the weight vector into the shear and normal components.

Kyphosis progresses with steady anterior force

Understanding the development of proximal junctional failure and kyphosis is critical for predicting patient outcomes and determining surgical strategies for adult spinal deformity. About 40% of patients fail to achieve a better quality of life after surgical fusion, highlighting the need for better understanding of spinal biomechanics.

Multiple metrics are currently used to help determine spinal alignment, all of which are scalar numbers that only provide measurements of angle or distance, rather than vectors (i.e., magnitude plus direction).

The sagittal vertical axis (SVA) —which provides overall spinal alignment based on radiographic spinal measurements — is most commonly used and best studied. It is insufficient for providing complete alignment goals, which also depend on gender, age, pelvic parameters and body weight.

The concept of “cone of economy” has long been used to understand global balance and its role in spinal deformity correction. If a patient’s global alignment falls outside this area, energy expenditure needs to increase to maintain balance.

Key to maintaining posture within the cone of economy is the integrity of the muscles and ligaments surrounding the vertebrae, i.e., the posterior musculoligamentous complex. This complex allows the spine to counteract the anterior shear force inherent in upright posture. Kyphosis develops as the posterior musculoligamentous complex weakens or as the anterior spine (intervertebral disc and vertebral body) collapses and shortens in height.


A common complication of long segment fusion of the spine is proximal junctional kyphosis. “Proximal junctional kyphosis is often associated with the shear weight vector being oriented anteriorly,” Dr. Habboub explains. “We conducted our study to quantify the forces acting upon the spine during upright posture into a two-component vector measurement (magnitude and angle) — the GSV — and thereby gain better insight into forces contributing to spinal imbalance.”

Study design

A retrospective review was conducted of 40 Cleveland Clinic patients with full-length spine radiographs available. Patients were categorized into one of four groups (n = 10 in each group) based on SVA, as follows: < 0 cm, 0 cm, 5 to 10 cm, and > 10 cm.

In addition to SVA, the following data were available: pelvic incidence, PROMIS-PH (Patient Reported Outcome Measurement Information System–Physical Health), age and body mass index (BMI).

GSV was calculated for each patient by plotting each vertebra from C2 to S1 on a local coordinate system centered on the midpoint of each vertebral body with the x-axis parallel to the endplates. Pitch — i.e., spinal rotation in the sagittal plane — was also used for analysis. GSV comprises two components:

  1. Total magnitude of the GSV (GSV-M), expressed in Newtons, i.e., the magnitude of the sum of weight shear vectors at each vertebra
  2. Overall angle of the GSV (GSV-A), expressed in degrees, i.e., the angle of the sum of weight shear vectors of each vertebra (compared with upright posture of 0° and anterior horizontal axis of 90° oriented toward the ground)

GSV calculations were automated using the Global Spine Vector application, which involves uploading a full-length spine radiograph, entering the patient’s weight and clicking on the midpoint of each vertebra.

Correlational analysis of the variables was performed using one-way ANOVA testing.

Key findings

The following findings support the strength of GSV for characterizing spinal deformity:

  • GSV-M and GSV-A were significantly different between the four SVA groups (P < .001).
  • GSV-A correlated strongly with SVA (Pearson correlation coefficient [R] = –0.82; P < .001) and moderately with PROMIS-PH (R = 0.5; P = .001).
  • GSV-M correlated well with SVA (R = 0.64; P < .001) and moderately or weakly with weight, age and PROMIS-PH.


Neither BMI nor pelvic incidence were significantly different between the various SVA groups.

Implications and future directions

Although GSV does not yet have an established clinical use, Dr. Habboub says it contributes in an important way to understanding the forces that determine posture, spinal alignment and balance. His group is conducting further research to evaluate its clinical utility, as well as collecting postoperative data to determine optimal ranges to help drive surgical decision-making.

“This study of novel spinal alignment metrics and their impact on posture represents a totally novel area of research,” notes study co-author Michael Steinmetz, MD, Chair of Cleveland Clinic’s Department of Neurosurgery. “Calculation of global shear vector enables the acquisition of more information than current spinal variables we collect, and it does so without need for the cumbersome manual measurement of angles.”


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