July 12, 2021

Resection of a Massive Pancreatic Adenocarcinoma

Seven-pound tumor requires complex, multidisciplinary care

Pancreatic Adenocarcinoma

Physicians at Cleveland Clinic Abu Dhabi removed a massive pancreatic adenocarcinoma from a 50-year-old woman after she was turned away from several other hospitals due to the size of the mass.


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Pancreatic adenocarcinoma is the most common form of pancreatic cancer. Patients typically have an extremely poor prognosis and only present with symptoms in the late stages of the disease. The patient had experienced symptoms for about a year, including a loss of appetite, diarrhea, weight loss, fatigue and excessive bloating. The tumor continued to grow, causing an abdominal bulge that made it difficult for her to sleep or perform daily activities. When the problem persisted, she underwent a biopsy that confirmed pancreatic adenocarcinoma. Other hospitals declined to perform the surgery due to the size of the mass.

“The complexity involved in removing a 3.5 kg mass meant that the other hospitals she visited found it challenging to handle the surgery. She was finally referred to Cleveland Clinic Abu Dhabi as her best hope,” says Dr. Naveed Ahmed, a hepatobiliary surgeon who was part of the multidisciplinary care team at Cleveland Clinic Abu Dhabi’s Digestive Disease Institute​.

“She was very weak when she arrived at the hospital and her stomach had expanded to an extent that she felt pregnant. This is because the large mass kept growing inside the abdomen and was intimately attached to the major vessels supplying the abdomen, liver and intestine. Another two to three months without treatment and it would have been too late.”

Resecting the tumor

The surgical team performed a near total pancreatectomy with vessel reconstruction.


“The size did pose a challenge, and we had to alter our usual technique of resection to preserve the main vessels that supply the gut. We then removed the cancer completely and reconstructed the vessels around the pancreas,” says Dr. Ahmed.

The patient is now undergoing chemotherapy and will require ongoing surveillance. The patient reports that she is recovering well and her quality of life has greatly improved since the removal of the mass.

The Digestive Disease Institute, one of the six Centers of Excellence at Cleveland Clinic Abu Dhabi, provides the most advanced level of medical and surgical care for disorders of the gastrointestinal tract, ranging from irritable bowel syndrome to gastrointestinal oncology.

The hospital continues to expand its range of cancer services as it prepares to open its dedicated oncology center in 2022. Modelled on Cleveland Clinic’s Cancer Center in Cleveland, the facility will provide a full range of advanced treatments in a central location and house support services designed to make patients as comfortable as possible as they receive their care.


Digestive care at Cleveland Clinic Abu Dhabi

The Digestive Disease Institute has more than tripled in size since its inception, with more than 46 physicians in gastroenterology, colorectal surgery and general surgery. Its subspecialty centers, in which physicians and surgeons work side by side, is unique in and has been warmly embraced by the region. A newly established surgical residency trains the next generation of United Arab Emirates physicians, who benefit from the institute’s close collaboration with Cleveland Clinic in Ohio and Florida, including weekly webinars, joint projects and papers and frequent exchanges.

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