An animal model of brachytherapy-induced retinopathy would help investigators understand the underlying pathophysiological mechanisms. Cleveland Clinic researchers are creating one, which could eventually help test promising therapeutics.
With certain retinal tears of 6 clock hours or more, the retina can fold on itself. In this case, optical coherence tomography showed the foveal pit not only detached, but also folded over in a “tidal wave” configuration.
Using a novel thermal laser injury model, researchers observed the earliest response to injury in the zebrafish retina. The hope is to one day make regenerative retinal therapy in humans a reality.
Cleveland Clinic successfully implanted the Argus II Retinal Prosthesis System in its first patient. Hear first-hand from our physician and her patient (VIDEO), who was completely blind from retinitis pigmentosa and has regained some vision.
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services Policy
Zebrafish are naturally able to heal damaged retinas and prevent scarring that can lead to loss of vision. Cleveland Clinic researchers hope to learn how to replicate that process in the human eye.