Our radiation oncologists have compiled a list of abstracts recently presented at the annual meeting of the American Society for Radiation Oncology that they consider to be the most intriguing, clinically relevant and transformative.
Cognitive Function Remains Stable Following Concurrent Temozolomide-based Chemoradiation Therapy in Low-Grade Gliomas
A study conducted in 22 adult patients with low-grade glioma found that concurrent temozolomide-based chemoradiation therapy does not adversely influence neurocognitive function during a 2-year treatment follow up.
Biosignature Predicts Benefit of Adjuvant Radiotherapy in Patients With DCIS
Results from a multi-institutional study led by a Cleveland Clinic researcher, DCSionRT®, a biosignature based on multiple biomarkers, may hold the key to solving the treatment of ductal carcinoma in situ (DCIS).
18F Fluciclovine PET CT Helps Distinguish Radiation Necrosis from Brain Tumor Progression
A prospective pilot study conducted in 16 patients with brain metastases found that 18F fluciclovine PET CT demonstrated promising utility in distinguishing radiation necrosis from tumor progression among patients treated with stereotactic radiosurgery.
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ASTRO Releases New APBI Guidelines: What Clinicians Need to Know (Video)
How will the ASTRO’s newly released updated guidelines for the off-protocol use of APBI affect your practice? Cleveland Clinic radiation oncologist Chirag Shah, MD, discusses the most significant changes.
Top 10 ASTRO Abstracts
Favorites chosen by Cleveland Clinic’s Radiation Oncology staff at the 2015 American Society for Radiology Oncology (ASTRO) annual meeting.
Study of Integrative Radiogenomic Profiling Identifies BRAF Mutations as Novel Radiotherapeutic Targets in Lung Adenocarcinomas
Lung tumors bearing the BRAF mutation are resistant to radiation therapy, but a new study finds they can be sensitized to it by commercially available MEK inhibitors. This could benefit 4-6 percent of patients with lung cancer.
Updated Nomogram Predicts Modern Outcomes After Salvage Radiotherapy Following Radical Prostatectomy
Early salvage radiotherapy after prostatectomy found to be associated with improved freedom from biochemical failure and distant metastases. Updated nomogram more accurately predicts patient outcomes.
Cleveland Clinic Researchers Develop Model to Help Predict Distant Metastases in Early-Stage Lung Cancer
Researchers at Cleveland Clinic develop a way to predict distant metastases in patients with early-stage lung cancer after stereotactic body radiotherapy using readily available patient variables.
Advanced Practice Nurses Help Reduce Adverse Events in Head and Neck Cancer Patients
Radiotherapy for head and neck cancer is associated with significant morbidity. A Cleveland Clinic study highlights the important role APNs can play in reducing adverse events after treatment with better follow-up care.