The first genome-wide association study of Parkinson’s disease in Latinos has identified several potential risk loci of interest in this understudied population.
Cleveland Clinic scientists have developed a solution to the locomotion problem in virtual reality (VR) to create an immersive VR experience to better understand and treat freezing of gait in Parkinson’s disease.
For the first time, this imaging tracer will be used in an attempt to detect neuroinflammation in the living brain in the setting of Parkinson’s and Alzheimer’s diseases.
No large-scale Parkinson’s disease genetic studies have ever been conducted in Latino populations — until now. The leader of the LARGE-PD cohort study explains its rationale and goals.
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BIIB054 takes aim at alpha-synuclein clusters. A leader of the global SPARK trial explains why it’s the most promising compound yet developed to fight early-stage Parkinson disease.
Alzheimer disease, Parkinson disease, normal aging and neuroinflammation are priority focus areas of the biobank, which aim to promote identification of novel biomarkers. The facility will benefit from Cleveland Clinic’s large, diverse patient population and neuroinflammation research expertise.
Deep brain stimulation (DBS) with real time intraoperative MRI lets surgeons assess lead location with anatomic landmarks instead of the microelectrode recording used during awake surgery. The intraoperative imaging allows DBS surgery to be done under general anesthesia, without patients needing to be awake for physiological measurements. Early Cleveland Clinic experience shows DBS leads implanted using intraoperative MRI varied only modestly from target placement, within expected error ranges.
Use of the C3Logix app to evaluate student athletes is growing as other applications emerge: managing mild traumatic brain injury in military personnel and testing cognitive function and postural stability in neurologic patients.