Imaging studies are offering a unique window into brain functional reorganization in prodromal HD that’s not related to brain atrophy or motor symptoms. Sensitive biomarkers of disease progression are the end goal.
Patients with cognitive impairment benefit from physical therapy, which not only can help improve gait and prevent falls, but also serves as a neuroprotector of further cognitive decline.
Cleveland Clinic has received an $8.75 million National Institute on Aging grant for a 150-patient study of how exercise might modify genetic risk for Alzheimer’s disease.
Can deep brain stimulation help ease motor and psychiatric symptoms of Huntington’s disease?
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In the first longitudinal study to compare brain activity and cognitive function in cognitively intact elders with and without a key gene marker for Alzheimer disease, fMRI demonstrated clear differences.
Cleveland Clinic’s self-administered Processing Speed Test app for iPad is at least as good as the existing technician-administered test at identifying cognitive dysfunction in MS patients. Its advantages could translate to more frequent and cost-effective patient monitoring.
Two recent functional neuroimaging studies advance our understanding of how the brain changes with concussion, raising the prospect of one day using fMRI for disability assessment and rehab planning.