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Genomic Medicine

DNA gel showing genetic sequencing
February 20, 2024/Neurosciences/Epilepsy

Large GWAS Meta-Analysis Identifies Multiple New Genetic Risk Factors for Epilepsy

Characterizing genetic architecture of clinical subtypes may accelerate targeted therapy

DNA

Is the MTHFR Gene Mutation Associated With Thrombosis?

The relationship between MTHFR variants and thrombosis risk is a complex issue, but current evidence points to no association between the most common variants and an elevated risk

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Microglial Immunometabolism Endophenotypes Implicated in Sex Differences in Alzheimer’s Disease

Study suggests sex-specific pathways show potential for sex-specific therapeutic approaches

Feixiong Cheng, MD

An All-Fronts Approach to Understanding and Overcoming Alzheimer’s Disease

A conversation with Feixiong Cheng, PhD, about his wide-ranging research initiatives

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HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial
October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

Genetic testing
June 16, 2023/Bioethics

The Cost of ‘Free’: Advising Patients About Sponsored Genetic Testing

Authors discuss ethical challenges associated with sponsored genetic testing

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Quantum Computing Debuts at Cleveland Clinic

Discovery Accelerator Partnership with IBM Deploys Advanced Computing Technologies to Supercharge Healthcare Research

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February 22, 2023/Genomic Medicine/Research

Determining Autism, Cancer Risk in Patients with PTEN Hamartoma Tumor Syndrome

Cleveland Clinic researchers receive $2 million grant from the National Institutes of Health

Brain research

Deep Learning Framework Unveiled for Identifying Risk Genes and Drug Targets in Alzheimer’s Disease

Open-source artificial intelligence technology uses human genetic data to find candidate drugs

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Transcriptomics-Based Study Suggests Metformin Is Repurposable for Atrial Fibrillation

Network proximity and EHR analyses identify diabetes drug as a top candidate for risk reduction

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