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Genomic Medicine

Dr. Imad Najm against a decorative background
September 16, 2024/Neurosciences/Podcast

Temporal Lobe Epilepsy and the Potential of Gene Therapy (Podcast)

Investigational gene approaches offer hope for a therapeutically challenging condition

gut-brain axis

Assessing Alzheimer’s Disease Drug Targets Along the Gut-Brain Axis

Pairing machine learning with multi-omics revealed potential therapeutic targets

DNA gel showing genetic sequencing
February 20, 2024/Neurosciences/Epilepsy

Large GWAS Meta-Analysis Identifies Multiple New Genetic Risk Factors for Epilepsy

Characterizing genetic architecture of clinical subtypes may accelerate targeted therapy

DNA

Is the MTHFR Gene Mutation Associated With Thrombosis?

The relationship between MTHFR variants and thrombosis risk is a complex issue, but current evidence points to no association between the most common variants and an elevated risk

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Multi-Ancestry Genetic Study of Parkinson’s Disease Identifies New Risk Genes in Pursuit of Novel Treatment Targets

International collaboration is most genetically diverse study of the disease to date

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Microglial Immunometabolism Endophenotypes Implicated in Sex Differences in Alzheimer’s Disease

Study suggests sex-specific pathways show potential for sex-specific therapeutic approaches

Feixiong Cheng, MD

An All-Fronts Approach to Understanding and Overcoming Alzheimer’s Disease

A conversation with Feixiong Cheng, PhD, about his wide-ranging research initiatives

HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial
October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

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August 17, 2023/Genomic Medicine

Parkinson’s Disease Research in Women (Podcast)

Studying gender-specific health factors promises new insight into diagnosis, prognosis, treatment

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July 3, 2023/Genomic Medicine

Genetics of Parkinson’s Disease in Latino Populations (Podcast)

Consortium is uncovering risk factors that spur disease development in an understudied group

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