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Genomic Medicine

gloved hand holding blood vial with neuropathology slide in background
October 10, 2025/Neurosciences/Epilepsy

Blood-Based Epigenetic Biomarkers Differentiate Focal Cortical Dysplasia Subtypes

Paired blood and brain tissue methylation findings raise prospect of noninvasive precision diagnosis

small RNA molecules

RNA Editing Characterized in the Aging Brain With Alzheimer’s Disease

Genomic study lays groundwork for insights into potential biomarkers and therapeutic strategies

herpesvirus cell in illustrated form

Herpesviruses May Contribute to Alzheimer’s Disease via Transposable Elements

Research combining genomics, database analysis and RNA sequencing suggests possible role for antiviral drug therapy

DNA double helix superimposed on transparent human brain

Researchers Identify Potential Risk Genes and Drug Repurposing Candidates in Parkinson’s Disease

Systems genetics approach sets stage for lab testing of simvastatin and other candidate drugs

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Medical illustration of microglia
December 10, 2024/Genomic Medicine/Research

Network-Based Analyses Uncover How Harmful Microglia Form in Alzheimer’s Disease

Study identifies Ketorolac as a potential repurposable drug

Dr. Imad Najm against a decorative background
September 16, 2024/Neurosciences/Podcast

Temporal Lobe Epilepsy and the Potential of Gene Therapy (Podcast)

Investigational gene approaches offer hope for a therapeutically challenging condition

gut-brain axis

Assessing Alzheimer’s Disease Drug Targets Along the Gut-Brain Axis

Pairing machine learning with multi-omics revealed potential therapeutic targets

DNA gel showing genetic sequencing
February 20, 2024/Neurosciences/Epilepsy

Large GWAS Meta-Analysis Identifies Multiple New Genetic Risk Factors for Epilepsy

Characterizing genetic architecture of clinical subtypes may accelerate targeted therapy

DNA

Is the MTHFR Gene Mutation Associated With Thrombosis?

The relationship between MTHFR variants and thrombosis risk is a complex issue, but current evidence points to no association between the most common variants and an elevated risk

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Microglial Immunometabolism Endophenotypes Implicated in Sex Differences in Alzheimer’s Disease

Study suggests sex-specific pathways show potential for sex-specific therapeutic approaches

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