Cognitive phenotypes are related to behavioral changes in Alzheimer’s and Lewy body dementia
Risk of agitation, delusions, personality change and more is shaped by early presentation
69% relative risk reduction in large database analysis prompts plans for mechanistic and phase 2 studies
$15.4M grant to fund work on atypical Alzheimer’s, Lewy body dementia and more
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Links are centered on neuroinflammation and microvascular injury, network medicine study finds
Longitudinal study implicates a specific pathway in mild cognitive impairment stage
$2 million will enable preclinical dose and efficacy testing of “compound 3”
Cleveland Clinic-developed “compound 3” begins testing in preclinical Alzheimer’s model
Third annual report shows shift toward prevention studies, disease-modifying therapies
Most substantial reversal of amyloid deposition in an animal study to date
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