New research shows that the sustained expression of YES1, a member of the Src family of protein tyrosine kinases, plays an important role in the growth, viability and genomic stability of triple-negative breast cancer cells.
Pathway that Mediates Cytotoxicity of AZA Discovered
We now know how 5-azacytidine (AZA) induces apoptosis in cancer cells, thanks to a deepened understanding of the OAS-RNase L pathway.
Seeing Asthma Differently with the 4Dx Scanner
Cleveland Clinic is only the second institution in the world to own the preclinical scanner and is the first to use it in the study of asthma.
Smooth Delivery: ADAMTS9 Enhances Uterine Smooth Muscle Contractions
A preclinical model shows that ADAMTS9 is important for effective uterine contraction during late stage pregnancy and delivery. In its absence, significant delivery complications occurred.
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The True Value of Basic Research
Nearly everything we do in the lab has an uncertain outcome, and therefore every experiment provides knowledge that is new in some way. Biomedical researcher Dr. Suneel Apte explains.