Cleveland Clinic Cancer Center investigators have published a body of research that may herald an era of improved staging and risk stratification for patients with Merkel cell carcinoma, utilizing distinct histologic patterns in sentinel lymph node biopsies.
Gene Profile Test Holds Predictive Potential for Early Stage Melanoma Patients
The 31-GEP identifies low-risk patients most likely to benefit from intensive surveillance and adjuvant therapy.
The Long Road to Cleveland Clinic’s First Total Face Transplant — and the Path Ahead
Our first total face transplant involved far more than a single 31-hour operation. Here are essentials of the patient’s unparalleled case and what lies ahead for her and the face transplant field.
The Biggest Moment in Cleveland Clinic’s First Total Face Transplant
One moment in the 31-hour operation stands out from the rest. Two of the surgeons share when, and why, the OR went from a hush to a collective sigh.
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Inside the OR in Cleveland Clinic’s Total Face Transplant: Tapping the ‘Collective Genius’ of the Team
Two surgeons from the procedure share how subjecting a key intraoperative choice to the ‘surgical court of law’ and family input ultimately yielded the best decision.
Case Series: Patients with Unresectable Melanoma Respond to New Combination Treatment
A rare case series in which real-world outcomes impress beyond trial results.
Timing of Melanoma Diagnosis, Treatment Critical to Survival
Treatment delay negatively impacts overall survival for patients with stage I melanoma.
Solar Radiation-Induced Changes in MicroRNAs May Trigger Melanoma Progression
Melanocytes in people with a history of melanoma react differently to solar radiation exposure than do melanocytes in healthy people, researchers have found. UV radiation can upset the balance of microRNA expression, causing regulatory and immune-response changes in cancer-prone cells that may represent the key first step in progression to melanoma.
Pregnancy Worsens Melanoma Prognosis
Cleveland Clinic researchers find that women diagnosed with malignant melanoma while pregnant or soon after giving birth have increased rates of death, metastasis and cancer recurrence.