Detailed findings from this large outcomes study of omega-3 carboxylic acid have renewed scrutiny over potential confounding effects of the mineral oil placebo used in the earlier REDUCE-IT trial.
We were recruiting patients for 75+ cardiovascular clinical trials when COVID-19 struck. Here’s how we’ve worked to keep as many of them on track as possible.
A veteran physician researcher shares tips on getting started in clinical trials, obtaining funding, following regulatory standards and making your research efforts a success.
A genotype found to be associated with reduced cardiovascular events in a study of dalcetrapib wasn’t associated with benefit in a trial of fellow CETP inhibitor evacetrapib.
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This substudy of the huge PRECISION trial shows that clinicians need to weigh the potential dangers of worsened blood pressure control when considering chronic use of NSAIDs — especially ibuprofen.
The ACCELERATE trial found no effect on cardiac events with evacetrapib despite large HDL gains and solid LDL declines. A substudy presented at ESC 2017 now shows the drug fared no better when analysis was limited to diabetic patients.
The transcatheter approach to aortic valve replacement in intermediate-risk patients appears to curb the risk of these potentially deadly effects, new subanalyses presented at ACC.17 show.
Make room in your schedule at the American College of Cardiology meeting for key presentations ranging from the SPIRE 1 and 2 trials to ABSORB III two-year results and more.
Long-standing hope for MDCO-216, which contains the ApoA-1 Milano variant of HDL, disappears as the compound fails to yield coronary plaque regression. But the jury’s still out on other HDL-targeted therapies.
Ketamine has emerged as an alternative to electroconvulsive therapy for treatment-resistant depression, but no study has compared the two. A major research project led by Cleveland Clinic is changing that.