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Research

gut microbes in the human intestine
August 30, 2024/Heart, Vascular and Thoracic/Preventive Cardiology

Gut Microbial TMAO Pathway Associated With Incident Heart Failure

Metabolites from animal product substrates implicated in heart failure development in community cohorts

chemical structure of erythritol drawn in a teaspoon
August 9, 2024/Heart, Vascular and Thoracic/Research

Evidence Mounts That Sugar Substitute Erythritol Raises Cardiovascular Risk

Study authors urge reevaluation of the sweetener’s safety designation by food regulators

x-ray of bone fracture in a forearm
March 1, 2024/Heart, Vascular and Thoracic/Research

TRAVERSE Substudy Links Testosterone Therapy to Increased Fracture Risk in Older Men With Hypogonadism

Surprise findings argue for caution about testosterone use in men at risk for fracture

photo of intubated elderly woman in hospital bed
February 23, 2024/Heart, Vascular and Thoracic/Research

Proteomic Study Characterizes Markers of Frailty in Cardiovascular Disease and Their Links to Outcomes

Findings support emphasis on markers of frailty related to, but not dependent on, age

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HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial
October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

GettyImages-1252287413 [Converted]
September 8, 2023/Heart, Vascular and Thoracic/Research

Black Residents of Historically Redlined Areas Have Increased Heart Failure Risk

Large database study reveals lingering health consequences of decades-old discrimination

23-HVI-4172009 CQD 650×450-2
August 29, 2023/Heart, Vascular and Thoracic/Research

Updates From CLEAR Outcomes and VALOR-HCM: Expanded Benefits With Bempedoic Acid and Mavacamten

Additional analyses of the two trials presented at 2023 ESC Congress

23-HVI-3972959_testosterone-and-the-heart_650x450
June 16, 2023/Diabetes & Endocrinology

TRAVERSE Study Supports Cardiovascular Safety of Testosterone Therapy When Used as Indicated

But findings apply only to middle-aged or older men with confirmed hypogonadism

23-HVI-3853878_aortic-aneurysm_650x450
May 17, 2023/Basic & Translational Science

Study Identifies Gut Microbe-Derived TMAO as a Novel Mediator of Abdominal Aortic Aneurysm

Findings hold implications for screening and potential nonsurgical therapy

23-HVI-3673794 CQD Hero 1a
April 17, 2023/Basic & Translational Science

Soft Robotic Model Replicates Patients’ Aortic Stenosis and Ventricular Dysfunction

Potential benefits include clinical guidance, TAVR outcome prediction, device testing

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