In the last 20 years, cases of pediatric nephrolithiasis have increased each year by an estimated 4 percent to 10 percent. Urologist Jeffrey Donohoe, MD, offers practical advice for managing them in your practice.
Antibiotics and a high-fat, high-sugar diet significantly and persistently inhibited microbial oxalate metabolism by gut microbiota in a mouse model. Important implications for kidney stone development and prevention.
Cleveland Clinic researchers compared the urinary metabolites of patients with and without urinary stones to explore whether we are losing metabolites that protect us from stones.
If a CT is ordered, let’s put it to good use. CTs for stones can also help identify comorbidities, predict metabolic abnormalities, identify who may benefit from dissolution therapy and devise preventive strategies – all at no additional cost.