Although cancer can damage the ovaries, leading to infertility and early menopause, young women with cancer have several options for fertility preservation. Gynecologic oncologist Mariam AlHilli, MD, discusses a case in which three different fertility preservation procedures were conducted to give a young woman her best chance at future fertility.
Gynecologic oncologist Mariam AlHilli, MD, explains recent research, which confirms that women under 40 with endometrial cancer have more favorable prognoses, though are more likely to recur. The study also found that mismatch repair protein deficiency caused by methylation of the gene MLH1 predicted a worse prognosis.
Delayed time-to-surgery has a negative impact on overall survival of women with early stage endometrial cancer, a recent study reveals. Contributors to delay include race, insurance status and facility type. Additional contributors may include increased frequency of preoperative diagnostic testing, individual surgeon case load, lack of surgeon access to a robotic surgery platform, or availability of specialist gynecologic oncologists.
Universal screening for endometrial cancer, begun in 2012 at Cleveland Clinic, has helped build one of the largest prospective cohorts of screened patients, providing fertile ground for studying Lynch syndrome.
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What clinicians need to know about using advances in next-generation sequencing to simultaneously test for multiple genes associated with hereditary cancers.