Case Report: Systemic Lupus Erythematosus and Pregnancy Planning

Before, during and after your patient's pregnancy

A 28-year-old female with systemic lupus erythematosus (SLE) with lupus nephritis presented to rheumatology clinic for preconception counseling. Her medications included mycophenolate mofetil, tacrolimus, hydroxychloroquine and lisinopril. She reported feeling well, and blood work showed normal renal functioning without any markers of disease activity.

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Since mycophenolate mofetil and lisinopril are considered teratogenic, the patient was counseled on controlling disease with pregnancy-compatible medications prior to attempts at conceptions. Watch below as Emily Littlejohn, DO, MPH, associate staff in the Department of Rheumatologic and Immunologic Diseases, provides details about alternative medications, ongoing monitoring during pregnancy and neonatal risk assessments for this patient and offers insights on general management of pregnancy planning in patients with SLE.