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Research

photo of intubated elderly woman in hospital bed

Proteomic Study Characterizes Markers of Frailty in Cardiovascular Disease and Their Links to Outcomes

Findings support emphasis on markers of frailty related to, but not dependent on, age

HVI_Kelley_4277155_Patient Procedure Shoot- First in Human Trial
October 27, 2023/Genomic Medicine

Cleveland Clinic Treats First Patient With Investigational Gene Therapy for Hypertrophic Cardiomyopathy

One-time infusion of adenovirus-based therapy is designed to restore heart muscle function

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TRAVERSE Study Supports Cardiovascular Safety of Testosterone Therapy When Used as Indicated

But findings apply only to middle-aged or older men with confirmed hypogonadism

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Hazen, MD, PhD

Study Identifies Gut Microbe-Derived TMAO as a Novel Mediator of Abdominal Aortic Aneurysm

Findings hold implications for screening and potential nonsurgical therapy

medical device with inset image

Soft Robotic Model Replicates Patients’ Aortic Stenosis and Ventricular Dysfunction

Potential benefits include clinical guidance, TAVR outcome prediction, device testing

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Transcriptomics-Based Study Suggests Metformin Is Repurposable for Atrial Fibrillation

Network proximity and EHR analyses identify diabetes drug as a top candidate for risk reduction

22-HVI-3200902 – CQD 650×450

Adjustable Soft Robotic Sleeve Mimics Complex Hemodynamics of Aortic Stenosis

Sophisticated in vivo modeling can enhance device development and therapy testing

Exercise

Novel Technologies Elucidate Underlying Causes of Exercise’s Benefit to the Heart

DT-MRI and RNA-FISH show increase in CITED4 promotes healthy architecture of myocardium

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Study Confirms Quality-of-Life Benefits of Myectomy in Obstructive HCM

Prospective SPIRIT-HCM trial demonstrates broad gains over 12-month follow-up

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